Poisons Flashcards

1
Q

What should you ask on the phone to a suspected poisoning?

A

What, when, dose?

Bodyweight

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2
Q

Who should you call for information about poisons?

A

Veterinary poisons information service - VPIS

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3
Q

What should the owner bring?

A

Product label/photo

Sample of product

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4
Q

What are the 5 main categories of the patient triage after poisoning?

A
Respiratory
CV 
Neuro
Urogenital
Other eg. abortion, dermatological
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5
Q

What are the 3 general principles of managing intoxication?

A

Remove/eliminate toxin
Reduce ongoing absorption
Dilution of toxin

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6
Q

What are the 4 main methods of removing/eliminating toxin?

A

Induce emesis
Gastric lavage
Cutaneous decontamination
Haemodialysis

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7
Q

When should you do emesis?

A

Within 2-3 hours after oral ingestion of a non corrosive agent

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8
Q

When is emesis contraindicated?

A

If corrosive/irritant
Pre-existing aspiration risk
If petroleum distillate

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9
Q

What are the two emetic agents? How are they administered?

A

Apomorphine - SC

Xylazine - IM

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10
Q

When should gastric lavage be used?

A

Within an hour

Induction of emesis unsuccessful

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11
Q

How is gastric lavage performed?

A

Under anaesthesia
Intubated
Lateral recumbency
Use gravity to lavage with warmed water/activated charcoal

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12
Q

How do you perform cutaneous decontamination?

A

Clip affected regions
Warm water
Mild shampoo/detergent

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13
Q

What are the two methods of reducing ongoing obsorption?

A

Enteric adsorbents

Intralipid

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14
Q

What is an example of an enteric adsorbent?

A

Activated charcoal

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15
Q

How are intralipids useful?

A

They bind to substances that have already been absorbed into the blood stream to prevent them from reaching the brain

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16
Q

What supportive management can be given for intoxication?

A
Specific antidote
Analgesia
Maintain hydration and nutrition
Manage nausea - antiemetics
Tremors - muscle relaxants
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17
Q

What can be given for hepatotoxins?

A

Antioxidant support

Lactulose

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18
Q

What substances should you not worry about?

A

Contraceptive pill
Silica gel
Catnip

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19
Q

What questions can you ask in a large animal suspected poisoning?

A

Onset/duration
Location of livestock
Nutrition/feeding
Any potential access

20
Q

What common toxins cause sudden death?

A

Yew
Lead
Water dropwort
Copper

21
Q

What common toxins cause neuro signs?

A

Ragwort
Lead
Ergot

22
Q

What common toxins cause GI signs - diarrhoea?

A

Oak - acorns
Ragwort
Rhododendron

23
Q

What common toxins cause resp signs?

A

Fog fever

24
Q

What is fog fever?

A

L-tryptophan - change in diet

25
Q

What common toxins cause CV signs?

A

Bracken

26
Q

What common toxins cause dermatological signs?

A

Photosensitisation
Molybdenum
St johns wart

27
Q

What common toxins cause urine discolouration/haematuria?

A

Bracken

28
Q

What does water dropwort look like?

A

Celery with white flowers

29
Q

When does copper poisoning usually occur?

A

Overdose when treating for deficiency/supplementation

30
Q

What does ragwort look like?

A

Celery with yellow flowers

31
Q

What is ergot?

A

Fungus growing on late sumer long grass grain

32
Q

How is fog fever treated?

A

Diuretics - frusemide

33
Q

What is photosensitisation?

A

Circulating chemicals absorb sunlight and damage skin

34
Q

What can cause photosensitisation?

A

Primary from direct action of ingested toxin eg. st johns wort
Secondary from damaged liver not breaking down toxic metabolites

35
Q

What does high molybdenum cause?

A

Copper deficiency signs - is a copper antagonist
Green diarrhoea
Poor coat
Poor fertility
Ill thrift

36
Q

What are the clinical sign of bracken poisoning?

A

Haemorrhage
Bladder/upper alimentary tract neoplasia
Haematuria
CV signs

37
Q

What are other causes of sudden death in cattle that should be considered?

A

Anthrax

Hypovolaemia

38
Q

What main symptom does rhododendron cause?

A

Projectile vomiting

39
Q

What does st johns wort cause?

A

Photosensitisation

40
Q

What does oak cause/

A

Colic/severe indigestion

41
Q

What does yew cause?

A

Sudden death

42
Q

What does ragwort cause?

A

Neurological signs via liver pathology
GI signs

43
Q

What does water dropwort cause?

A

Sudden death

44
Q

What can cause severe hind limb lameness progressing to distal limb necrosis?

A

Ergot

45
Q

What mineral is high on the Somerset levels causing ill thrift and scour?

A

Molybdenum