Bovine reproduction Flashcards
What is the definition of fertility?
The ability of a cow to give birth to a live calf at approximately 12 month intervals
What is the definition of sterility?
The total inability of a cow to become pregnant/give birth to a live calf
What is infertility/subfertility?
Cow can become pregnant and give birth to a live calf but the interval may be longer than 12 months
What are some main reproductive difficulties?
Failure to cycle Failure to be mated Failure to conceive Dystocia Stillbirths Neonatal mortality
What are the two things that can happen to a follicle?
Ovulates or atreses
How long is a normal cow oestrous cycle?
21 days
What is a normal post partum cyclicity pattern?
3 weeks post partum - small rise in progesterone due to an short lived corpus luteum
Then goes into a normal 3 week cycle
What other post partum cyclicity patterns are there?
Long anoestrus - suckling calf
Persistent luteal phase - abnormal
What is involution of the uterus?
Repairing the uterus
How long do you have to get the cow back pregnant for the 12 month cycle?
85 days
When is puberty in heifers?
7-18 months
35-40% of mature body weight
What is the age that cows are first served?
14-22 months
Best to calve at 2 years
What is the average duration of oestrus?
6 hrs
How and when do cows ovulate?
Spontaneously 9-15hrs after the end of standing oestrus
When is it best to inseminate a cow?
6 hrs
At mid oestrus
What is a common cause of poor reproductive performance?
Poor oestrus detection
What are the most reliable signs of oestrus?
Standing to be mounted
Mounting the head and neck of other cows
When is the first post partum oestrus?
15-30 days after calving
What is the first post partum oestrus like?
Behavioural oestrus is absent bcos brain needs to be primed with progesterone
What should the BCS be at calving?
3 so it doesnt drop below 2.5 at service
What is the average length of gestation?
285 days
How long is the gestation period to be considered abortion?
Shorter than 270 days
Why should you perform a breeding soundness exam on a bull?
Can cause major financial impact on a farm
Welfare
When should you perform a breeding soundness exam?
Pre purchase
Pre breeding season
For an infertility investigation
What are the steps of a breeding soundness exam?
Take history Clinical exam Semen collection/evaluation Test mating Prognosis
What are the 4 different categories of inability to mate?
Good libido but hesitant about mounting
Failure to exteriorise penis
Penis exteriorised but no intromission
Intromission but no thrusting
What can cause no thrusting?
Damage to the dorsal nerve of the penis - dont know penis is in vagina
How can you examine the penis safely without causing damage?
Xylazine - relax retractor penis muscle
Before/after mating - deviate to one side and look
What is the most common traumatic condition of the bovine penis?
Penile haematoma
What can cause penile haematoma?
Sudden angulation of penis/miss thrust
Tears tunica albuginea of corpus cavernosum at sigmoid flexure
What are the signs of penile haematoma?
Swelling cranial to scrotum
reluctance to serve, cant extrude penis
What is a complication of penile haematoma?
Abscessation
Damage to dorsal nerve of penis
Cant raise blood pressure in penis and get erection
What occurs to the penis normally during intromission?
Deviates ventrally and to the right
What is the main sign of spiral deviation of the penis?
Failure to extrude penis
What is phimosis?
Stricture of the preputial orifice
What does phimosis cause?
Failure to extrude the penis
What can cause phimosis?
Injury or infection
What is paraphimosis?
Can get the penis out of the prepuce but cant withdraw it
What does paraphimosis lead to?
Strangulation
What is balanoposthitis?
Inflammation of the penis and prepuce
What can cause balanoposthitis?
Infection
Trauma
BHV 1
Mycoplasma
What is the name of warts on the penis?
Fibropapilloma
What are signs or papilloma?
Bleeding at service
Pain at intromission
Phimosis/paraphimosis
What is impotence?
Cant get an erection
What are the two reasons for impotence?
Shunt for the blood
Blockage of proximal penis
What are some causes of impotence?
Congenitally large veins draining penis
Traumatic injury
Blockage by fibrous tissue/thrombus/haematoma
How do you assess the musculoskeletal system of bull?
Observe gait and posture
Lameness
Conformation
What change to the testes can cause infertility?
If held high/too close to body they will be too hot
What should testes be?
Similar in size
Round
Not too close to body
Symmetrical
What can cause testicular hypoplasia?
Inherited defect
XXY chromosome
What is a feature of testicular degeneration?
Failure of spermatogenesis
What can cause testicular degeneration?
Systemic infection
Trauma
Hot/cold
Autoimmunity
What are the 4 main causes of an enlarged testicle?
Orchitis
Abcess
Haematoma
Neoplasia
What can cause orchitis?
Wound
Ascending infection
Truporella pyogenes
What are the main features of orchitis?
Usually unilateral
Often accompanied by periorchitis/epididymitis
What is epididymal occlusion?
Blocked epididymis
What can epididymal occlusion cause?
Spermatocoele - cystic dilation
Sperm granuloma after rupture of epididymal wall
Testicular degeneration
What is seminal vesiculitis?
Normal penis and testes but abnormal ejaculate with not enough seminal fluid
What are the signs of acute seminal vesiculitis?
Severe pain
Purulent discharge
Pus in semen
Enlarged
What are the signs of chronic seminal vesiculitis?
Pus in semen
Fibrosis
Loss of lobulations
No pain
How do you collect semen?
Electroejaculation
Artificial vagina
Massage ampulla per rectum
What should you assess in semen evaluation?
Volume Colour Wave motion Motility - linear Live:dead ratio
What does semen evaluation show?
Potential to sire calves
Only true test is calves on the ground
How do you sex sperm?
Sort using flow cytometry - female sperm contain more DNA than male
What is the definition of abortion?
Production of one or more calves less than 271 days after service/AI
They are dead or alive for less than 24 hours
When is the level of abortion frequency an issue?
When it exceeds 3-5%
How are infectious agents of abortion classified?
Sexually transmitted
Non sexually transmitted
Primary - act directly on the repro tract
Secondary - cause systemic disease
What action should be taken following abortion?
Must report to DEFRA (not all investigated tho)
Isolate cow and calf
What are the main causes of viral infectious abortion?
BVD
BHV-1
Schmallenberg virus
What are the main bacterial causes of infectious abortion?
Bacillus licheniformis Lepto Salmonella Campylobacter fetus venerealis Mycoplasma Coxiella burnetii (Q fever)
What protozoa can cause infectious abortion?
Neospora caninum
What are 3 reasons that cause of abortion cant be identified?
Cause occured much earlier
Foetus retained for a while
Foetal membranes not available
What are the most common causes of infectious abortion?
Bacillus licheniformis Neospora caninum Trueperella pyogenes Schmallenberg aspergillus fumigatus Salmonella dublin Bovine viral diarrhoea Listeria
How can BHV-1 be transmitted?
Venereally
What are the main features of leptospirosis?
Abortion
Infertility
Milk drop
Zoonotic - flu-like
When should you vaccinate against lepto?
Turnout at spring
With antibiotics to remove infection
How do you diagnose salmonella abortion?
Cotelydons/foetal stomach contents
Where is bacillus licheniformis found?
Mouldy hay, silage
How is bacillus licheniformis diagnosed?
Gross appearance of placenta, isolate
How is campylobacter foetus transmitted?
Venereally from bull
How is campylobacter foetus diagnosed/noticed?
Repeat breeders
Vaginal microscopic agglutination
Semen exam
How is campylobacter treated?
Antibiotics
Penile irrigation
What is the main sign of mycoplasmosis?
Granular vulvovaginitis
Abortion
What are the clinical signs of Chlamydophila psittaci?
Early embryonic death
Abortion in late pregnancy
How is brucella transmitted?
Ingestion - most common
Venereally
What can brucella cause?
Abortion storms
What must be done when diagnosing brucella?
Report to DEFRA
Take swabs
How is brucella controlled?
Monthly bulk milk test
What is the most common cause of mycotic abortion?
Aspergillus
What are signs of mycotic abortion?
Placentitis/endometritis
Retained placenta
How is neospora transmitted?
Dog to cow
Vertically - cow to calf
What does neospora cause?
Midterm abortion and mummification
How do you control neospora?
Cull infected cattle
Restrict dog access
What is trichomoniasis?
Protozoa
How is trichomonas transmitted? How can it be controlled?
Venereally
AI
What are some non infectious causes of abortion?
Genetic, twin pregnancy, stress, nutritional deficiency, hypothyroidism, drug induced - PROSTAGLANDINS
What counts as early embryonic death?
Dies before day 15
Repeat breeders
What counts as late embryonic death?
Embryo dies between days 15 and 42
Irregular oestrus interval
What counts as foetal death?
Between day 43 and term
What can foetal death cause?
resorption, abortion, mummification, maceration
What occurs during foetal mummification?
Foestus dies and dehydrates
CL persists
Pseudopregnant, doesnt calve at expected time
No udder development
How do you treat foetal mummification?
PGF2a - to induce oestrus
What is foetal maceration?
Incomplete process of abortion
When does foetal maceration occur?
Occurs after third month of gestation
What occurs during foetal maceration?
Partial dilation of cervix
Allows bacteria in
Bacteria break down foetal soft tissues and leave bones
How is foetal maceration treated?
Usually culled
May be able to surgically remove
What is hydrops?
Excessive accumulation of foetal fluids
What is hydramnios?
Failure of swallowing of foetal fluids by the foetus causing hydrops
What is hydrallantois?
Failure of the selective resorption of elecrtolytes from allantois causing hydrops
How do you treat hydrops/hydrallantois?
PGF2a - induce abortion
May need c section
What can cause uterine rupture?
Mismanagement of dystocia
What are the signs of uterine rupture?
cessation of labour, shock, pain, haemorrhage
What can cause vaginal prolapse?
Breed
Overfeeding
Lack of exercise
How do you treat vaginal prolapse?
Epidural
Purse string suture
How is foetal maceration treated?
Usually culled
May be able to surgically remove
What are some signs of impending calving?
Increased udder development
Relaxation of pelvic ligaments, perineum and vulva
Oedema of ventral abdominal wall
What hormone is produced by the hypothalamus during parturition?
Corticotrophin releasing factor CRF
What hormone is produced by the pituitary grand during parturition?
Adrenocorticotrophin hormone
What hormone is produced by the adrenal grand during parturition?
Cortisol
What hormone is produced by the placenta during parturition?
Oestrogen
Prostaglandin
Some progesterone
What causes increase in oxytocin production from the pituitary gland during parturition?
Increased pressure on cervix and vagina from increased contractions
What are the two biggest causes of dystocia?
Foetopelvic disproportion - big calf small heifer
Foetal disposition
What are the signs of the second stage of parturition?
Rupture of allantochorion – allantoic fluid escapes
What are the signs of the third stage of parturition?
Uterine contractions
Placental detachment
Umbilical rupture Cotyledon detachment
When in gestation can parturition be induced in cows?
After 260 days of gestation
What drugs should you use to induce calving before 100 days of gestation?
PGF2a
What drugs should you use to induce calving 250-275 days into gestation?
Corticosteroid
What drugs should you use to induce calving after 275 days of gestation?
Corticosteroid plus PGF2a
How can you treat vaginal/uterine tears?
Clamp and stitch
Slaughter maybe
What does clenbuterol do?
Relaxes uterus at parturition
Help with dystocia/C section etc.
What can you give to aid with intense straining during dystocia?
Epidural
What is a foetotomy?
Removal of body parts via a saw which hindered the expulsion of the foetus
Which breeds have a disposition for uterine torsion?
Brown swiss and hostein
What is the most common uterine torsion?
90 degrees
How do you treat uterine torsion?
Rock calf as cow is standing, C-section, laparotomy
How do you treat post partum haemorrhage of uterus/vagina/placenta?
Ligate
Clamp
Pack
Oxytocin
What is uterine prolapse associated with?
Prolonged parturition
Hypocalcaemia
How can you treat uterine prolapse?
IV Ca2+ Epidural Invert uterus NSAIDs Oxytocin Suture vulva
What does gluteal nerve paralysis cause?
weak hindlimbs
What does obturator nerve paralysis cause?
Splay laterally
What is lochia?
Post partum discharge
Sloughing of tissue from caruncles
Reddish brown and odourless
What are the common bacteria that invade the uterus post partum when the cervix is still open?
T pyogenes
E coli
Staphs and streps
What can bacterial invasion of the uterus cause?
Acute metritis
Chronic endometritis
How can bacterial invasion of the uterus affect fertility?
killing conceptus, alter uterine milk, endometritis, delay onset of ovarian cyclicity
What is acute metritis?
Bacterial infection following dystocia
Associated with retained placenta
How do you treat acute metritis?
Broad spectrum antibiotic
IV fluids
NSAIDS
What is endometritis?
Inflammation of the endometrium
How does endometritis present?
Mucopurulent vaginal discharge - whites
When does endometritis present ?
21 days or mroe after calving
How can you treat endometritis?
PGF2a - return to oestrus, terminate CL
Intrauterine antibiotics
Saline washout
How can you diagnose pyometra in cows?
Ultrasound - thick uterine wall
What antibiotic do you give for endometritis?
Metricure - cephapirin/cephalosporin
What are retained foetal membranes? How long are they retained for?
Partial or complete retention beyond 12 hours post partum
What causes retained foetal membranes?
Failure of normal separation of foetal cotyledonary villi from maternal caruncles
What can predispose to retained foetal membranes?
premature parturition, placentitis, uterine inertia
What can retained foetal membranes cause?
Acute metritis
May just cause spontaneous expulsion
How can you treat retained foetal membranes ?
Antibiotics - Oxytetracycline
Manual removal - not ideal
What is a cystic follicle in cystic ovarian disease?
Persistent anovulatory follicle like structure
What are features of a follicular cyst?
Thin walled
Non progesterone producing - irregular/oestrous behaviour or anoestrus
What are features of a luteal cyst?
Thicker walled
Progesterone producing - anoestrus
How can you treat cystic ovarian disease?
GnRH/hCG - mimic LH surge to lutenise the structure
PGF2a
What is false anoestrus?
Oestrus not observed/detected
What is true anoestrus?
Interference with GnRH/LH
What can cause anoestrus?
Inadequate energy intake Suckling Delayed uterine involution Cystic ovarian disease Persistant CL
How can you treat anoestrus?
PG injection
CIDR or PRID plus PGF2a - mimic CL, then remove
What hormone treatments will enhance fertility?
GnRH holding injection
Chorionic gonadotrophin
PRID/CIDR - then remove
All at day 12
What is a repeat breeder cow?
Cow that fails to become pregnant following 3 or more consecutive services at normal interoestrus intervals
What causes repeat breeders?
Failure of fertilisation
Early embryonic death
How do you treat repeat breeders?
Improve condition
Holding injection