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CVSOH BVSc3 > Antiarrhythmic drugs > Flashcards

Antiarrhythmic drugs Flashcards

1
Q

What action do calcium channel blockers have on the heart?

A

Slows conduction through the AV node

For arrhythmias originating above the AV node

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2
Q

What is the hierarchy of pacemaker cells?

A

SAN
AVN
Bundle of his
purkynje fibres

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3
Q

What is the main sodium channel blocker that acts ONLY on ventricular action potentials?

A

Lidocaine

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4
Q

What are the main sodium channel blockers that acts on atrial and ventricular action potentials?

A

Procainamide

Quinidine

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5
Q

What can cause an arrhythmia?

A

Structural/ electrical remodelling
Haemodynamics
Endocrine issues

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6
Q

What is the definition of automaticity?

A

Spontaneous rhythmic depolarisation of cells in the conduction system

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7
Q

What are afterdepolarisations?

A

Oscillations during repolarisation

Can trigger sibsequent action potentials

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8
Q

Where do supraventricular arrhythmias originate?

A

In SAN, atrial myocardium or AVN

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9
Q

Where do ventricular arrhythmias originate?

A

Bundle of His
Purkynje system
Ventricular myocardium

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10
Q

What are class I antiarrhythmic drugs?

A

Sodium channel blockers

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11
Q

What are class II antiarrhythmic drugs?

A

Beta blockers

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12
Q

What are class III antiarrhythmic drugs?

A

Potassium channel blockers

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13
Q

What are class IV antiarrhythmic drugs?

A

Calcium channel blockers

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14
Q

What are the 3 main Na channel blockers?

A

Lidocaine
Procainamide
Quinidine

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15
Q

What is the main beta blocker?

A

Atenolol

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16
Q

What are the main potassium channel blockers?

A

Sotalol

Amiodarone

17
Q

What is the main calcium channel blocker?

A

Diltiazem

18
Q

What is quinidine used for?

A

Horses with atrial fibrillation

19
Q

What is procainamide used for?

A

Supra/ventricular arrhythmias in small animals

20
Q

What is lidocaine used for?

A

Life threatening ventricular arrhythmias

21
Q

What do beta blockers do?

A

Reduce HR - slow conduction
Decrease heart contraction
Reduce spontaneous depolarization

22
Q

What arrhythmia are beta blockers used for?

A

Arrhythmias mediated by sympathetic tone

23
Q

What shouldnt you do/use beta blockers for?

A

Dont use in heart failure

Slowly wean

24
Q

What do potassium channel blockers do?

A

Prolong refractory period and action potential duration

Suppress tachyarrhythmias

25
Q

What are potassium channel blockers used for?

A

Supra/ventricular arrhythmias

26
Q

What do calcium channel blockers do?

A

Reduce automaticity, slow AVN conduction, prolong refractory period

27
Q

What are calcium channel blockers used for?

A

Supraventricular tachyarrhythmias eg. atrial fibrillation, atrial tachycardia

28
Q

What is digoxin?

A

A parasympathomimetic
Decreases SAN firing
Slows AVN conduction

29
Q

What is digoxin used for?

A

Atrial fibrillation

CVSOH BVSc3 (60 decks)

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