Obstetrics 4 Flashcards
_______ is indicated for induction or augmentation of labor, stimulating uterine contraction (c-section), and combating uterine hypotonia and hemorrhage
Oxytocin
Side effects of oxytocin include
water retention, hyponatremia, hypotension, reflex tachycardia, and coronary vasoconstriction
Rapid IV administration of oxytocin can cause
cardiovascular collapse
The second-line uterotonic is typically
Methergine
Methergine is administered
IM
If methergine is given IV it can cause
significant vasoconstriction, hypertension, and cerebral hemorrhage
Prostaglandin F2 side effects include
N/V, diarrhea, hypotension, and bronchospasm
The dose of methergine is
0.2 mg IM
The half-life of methergine is
2 hours
Methergine is metabolized
hepatically
The third line uterotonic is
Prostaglandin F2 (hemabate or carboprost)
The dose of prostaglandin F2 is
250 mcg IM or injected into the uterus
During a C-section, oxytocin is administered
after the delivery of the placent
The half-life of oxytocin is
4-17 minutes
Oxytocin is metabolized
hepatically
Oxytocin is primarily synthesized in the
paraventricular nuclei of the hypothalamus
Oxytocin is stored in and released from
the posterior pituitary gland
Endogenous oxytocin is released following stimulation of
the cervix, vagina, and breasts
____ is the synthetic equivalent of oxytocin
Pitocin
Anesthetic implications for cesarean section under general anesthesia include:
a. administration of a dopamine agonist
b. prolonged neonatal respiratory depression
c. increased MAC
d. rapid sequence induction
D.
What situations would be appropriate for a general anesthetic for a Cesarean delivery?
maternal hemorrhage
fetal distress
coagulopathy
patient refusal of regional anesthesia
contraindications to regional anesthesia
In the obstetric population, mortality is ________ with a general anesthetic
17 x higher