Cardiovascular anatomy & physiology 2 Flashcards
What is the expected oxygen delivery in a 70-kg adult?
a. 20 mL/dL
b. 1000 mL/min
c. 250 mL/min
d. 15 mL/dL
b. 1000 mL/min.
_____________ tells us how many grams of oxygen are contained in a deciliter of arterial blood.
Oxygen content (CaO2)
What is the oxygen content equation?
CaO2= (Hgb x SaO2 x 1.34) + (PaO2 x 0.003)
What is the estimated oxygen content for a 70 kg male?
20 mL/dL
__________ tells us how much O2 is carried in arterial blood and how fast it’s being delivered to the tissues.
Oxygen delivery
What is the oxygen delivery equation?
Do2= Cardiac output x [(Hgb x SaO2 x 1.34) + (PaO2 x 0.003)] x 10
What is the estimated oxygen delivery in a 70 kg male?
1000 mL
__________ tells us how much oxygen is extracted by the tissues.
The oxygen extraction ratio (EO2)
What is the estimated oxygen extraction ratio?
25%
_____ tells us how much oxygen is consumed by the tissues
Oxygen consumption (VO2)
What is the estimated oxygen consumption?
250 mL/min or 3.5 mL/kg/min
_____________ tells us how much oxygen is carried in venous blood
Venous oxygen content
What is the estimated venous oxygen content?
15 mL/dL
Blood flow is inversely proportional to:
a. body temperature
b. vessel diameter
c. arteriovenous pressure difference
d. hematocrit
d. hematocrit
What is the basic equation for flow?
flow = (P1-P2)/resistance
Poiseuille’s law is an adaptation of Ohm’s law that incorporates
vessel diameter
viscosity
tube length
The best way to impact flow is to change
the radius because flow is directly proportional to the radius raised to the 4th power
Vascular resistance is primarily determined by the
radius of the arterioles
____________ can be used to predict if the flow will be laminar or turbulent
Reynolds’ number
Reynolds number <2000 predicts that flow will be
mostly laminar
Reynolds’ number >4000 predicts that flow will be
mostly turbulent
Reynolds 2000-4000 suggests
transitional flow
The vibrations that occur with turbulent flow can
produce a murmur (valvular heart disease) or bruit (carotid stenosis)
Blood viscosity is directly proportional to _______________- and inversely proportional to _______________
hematocrit; body temperature
When administering PRBCs, we can improve flow by
diluting the unit with normal saline and running it through a warming device
What are the 5 components of Poiseuille’s Law?
radius
Q= blood flow
length
viscosity
Arteriovenous pressure gradient (Pa-Pv)
Normal cardiac output is
5-6 L/min.
Normal stroke volume is
50-100 mL/beat
Normal ejection fraction is
60-70%
Normal MAP is
70-105 mmHg
Normal systemic vascular resistance is
800-1500 dynes x sec x cm-5
Normal pulmonary vascular resistance is
150-250 dynes x sec x cm-5
What is the formula for cardiac output?
HR x SV
What is the formal for cardiac index?
CO/BSA
What is the normal value of cardiac index?
2.8-4.2 L/min/m2
What is the equation for stroke volume?
EDV-ESV
or CO x 1000/HR
What is the formula for stroke volume index?
SV/BSA
What is the normal value for stroke volume index?
30-65 mL/beat/m2
What is the ejection fraction formula?
SV/EDV x 100
or
EDV-ESV/EDV x 100
What is the MAP formula?
(1/3 x SBP) + (2/3 x DBP)
(CO X SVR)/80 X CVP
What is the pulse pressure formula?
SBP-DBP
or stroke volume output/arterial tree compliance
What is the normal value of pulse pressure?
40 mmHg
What is the formula for systemic vascular resistance?
MAP-CVP/CO X 80
What is the formula for systemic vascular resistance index?
MAP-CVP/CI X 80
What is the normal value of systemic vascular resistance index?
1500-2400 dynes x sec x cm-5/m2
What is the formula for pulmonary vascular resistance?
MPAP-PAOP/CO x 80
What is the formula for pulmonary vascular resistance index?
MPAP-PAOP/CI x 80
What is the normal value for pulmonary vascular resistance index?
250-400 dynes x sec x cm-5/m2