Nutritional Pharmacology - Effects on Different Diets

Question 1

How can diet influence drug absorption and efficacy?

Answer 1

Diet can influence drug absorption and efficacy, such as high-fiber diets potentially reducing drug effectiveness.

Question 2

How does soy affect the absorption and efficacy of certain medications?

Answer 2

Soy decreases the absorption of levothyroxine; ingestion should be separated by 3 hours.
It can interfere with estrogen-blocking drugs like tamoxifen due to its isoflavone (phytoestrogen) content.
It may also reduce the effectiveness of warfarin.

Question 3

Q3: What is the interaction between dairy produce/calcium and medications?

Answer 3

Calcium can bind to antibiotics (e.g., quinolones, tetracyclines) and bisphosphonates, reducing their absorption.
It can also reduce levothyroxine absorption, so they should be taken 4 hours apart.

Question 4

Q4: How does a high-protein diet affect certain medications?

Answer 4

High-protein diets may reduce the effects of theophylline by increasing its renal clearance.
It may also reduce L-Dopa absorption by decreasing its intestinal absorption