Diagnostics - Microbiome Testing: Flashcards
What is a microbiome?
A microbiome consists of ecological communities of microorganisms (bacteria, archaea, protists, fungi, viruses) that live on all multicellular organisms.
Where are microbiomes found in the body?
Microbiomes are found in different niches, such as the gastrointestinal (GI) tract, vaginal area, oral cavity, skin, and urinary system.
What influences microbiome balance?
Microbiome balance is influenced by cultural, dietary, environmental, and familial factors, aligning with the terrain concept in health and disease.
How does the microbiome relate to health and disease?
The balance of the microbiome plays a critical role in influencing both health and disease.
What did Hippocrates say about the gut, and how is it supported today?
Hippocrates said, “all disease starts in the gut,” a statement that is supported by modern microbiome science.
What has recent technology done for stool testing?
Advances in stool testing technology have made it more accessible and accurate, enabling better evaluation of microbiome health.
What can stool testing help optimize?
Stool testing helps optimize microbiome health by evaluating diet, intestinal permeability, inflammation, gas-producing bacteria, or by identifying pathogenic microbes.
What does the term “commensal” mean?
“Commensal” refers to microbes that live harmoniously with the host, providing benefits.
What is a pathogenic microbe?
Pathogenic microbes are those with evolutionary advantages that harm the host.
What is a pathobiont?
A pathobiont is a microbe that is usually harmless but can cause problems if given the opportunity, such as in certain conditions.
What are gram-negative bacteria?
Gram-negative bacteria are bacteria with an outer cell wall rich in lipopolysaccharides (LPS).
What is LPS and what can it cause?
LPS, or lipopolysaccharide, is a major component of gram-negative bacteria that can cause inflammation and immune responses in the host.
