Module 6-drug use in animal production Flashcards

1
Q

what are some reasons drug are used in animal roduction

A

Many drugs are used therapeutically to control sickness and disease; untreated animals can spread contagious diseases to other animals, their productivity is reduced or they may die and costs of production will increase. The treatment of sick animals is a requirement of animal welfare. Some drugs are used to promote growth; such drugs decrease the cost of production and the price the consumer must pay for animal products

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2
Q

what is a major concern with antibiotics

A

rampant use of antibiotics in human and animal medicine has contributed to the development of antibiotic-resistant strains of bacteria that threaten our well-being and the well-being of animals as the antibiotics that we have been depending on since penicillin was discovered in 1928 cease being effective

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3
Q

what can lead to antibiotic-resistant bacteria

A

excessive use of antibiotics in livestock production, as well as the use of sub-therapeutic doses of antibiotics, can contribute to the development of antibiotic-resistant bacteria

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4
Q

how have Antimicrobials been used in livestock production

A

therapeutically, metaphylactically, prophylactically and to promote growth

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5
Q

what gives antimicrobials the greatest opportunity to become resistant

A

Sub-therapeutic doses of antimicrobials administered over a long period of time provide the greatest opportunity for pathogens to develop resistance to the antimicrobials.

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6
Q

how are antimicrobials used sub-therapeutically, i.e. for prophylaxis or growth promotion administered

A

they are administered at 10 to 50% of the therapeutic dose over a prolonged period

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7
Q

when the purpose is therapeutic or metaphylactic how are doses of antimicrobials administered

A

high doses are administered for a relatively short period of time

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8
Q

when antimicrobials are used Therapeutic what is the purpose of this

A

to treat clinically identified disease on either an individual basis or a group basis with antimicrobials added to the water or feed

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9
Q

what is the purpose of using antimicrobials for Metaphylactic reasons and how is it done

A

To prevent the spread of identified infection to cohorts; all animals are treated when the disease has been identified in some of the animals

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10
Q

what is the reason for using antimicrobials for Prophylactic reasons and how is it done

A

To control or prevent infection at times of increased risk such as immediately following weaning

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11
Q

what is the purpose of using antimicrobials for growth promotion

A

To increase growth and production efficiency by reducing intestinal colonization by opportunistic and overt pathogens; may be used in any or all stages of production; includes a prophylactic component

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12
Q

where and when were antimicrobials used to promote growth

A

Antibiotics have been used to promote growth in both the poultry and hog industries in the past; these practices were eliminated in Canada in 2018.

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13
Q

where is prophylactic use of antimicrobials common how has it changed

A

Prophylactic use, also previously common in the nursery phase of hog production has dramatically decreased as the administration has been restricted to high-risk animals

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14
Q

how has the use of metaphylactic antibiotics changed

A

Metaphylactic use of antibiotics in beef feedlots is now restricted to high-risk animals.

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15
Q

what has reduced the use of antimicrobials in most of the ivestock sectors

A

Changes to requirements for subtherapeutic administration of antibiotics which create the greatest opportunities for the development of antimicrobial resistance and require prescriptions for other antibiotics have reduced the use of antimicrobials in most of the livestock sectors.

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16
Q

before it became harder to purchase antimicrobials were we eating animals with antimicrobials in their system

A

no, Regardless of whether or not antimicrobials were being used, no animals were slaughtered for human consumption after receiving antimicrobials until after the withdrawal time for that antimicrobial had passed.

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17
Q

do we know the exact cause of antibiotic resistants

A

The use and misuse of antibiotics in both human medicine and the agriculture sector can be factors leading to widespread antibiotic resistance but the actual source of the resistance is very difficult to unequivocally determine since animals or people may act as reservoirs for resistant organisms derived from a different source. The relationship between sources of antibiotic resistance, reservoirs for antibiotic-resistant microbes and transmission between them is complex

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18
Q

in Denmark, there was a ban on antibiotics in the swine industry. what observations were made after this was put into effect

A

The reduction in antibiotic use in swine in Denmark has resulted in decreased performance and animal welfare and increased cost for the nursery phase of production while no major effect has been observed in the growing/finishing phase

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19
Q

what are some new antibiotic guidelines in north america

A

new guidelines for antibiotic use have been created and surveillance for antibiotic-resistant organisms in food animals and pets has been increased. New regulations limit the use of antimicrobials that are important in human medicine in food and companion animals. “Prudent Use” guidelines that include limiting subtherapeutic use have been developed and alternative methods for protecting animal health and promoting growth are being researched

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20
Q

what hare antibiotic-free farms

A

A small percentage of producers have completely removed antibiotics from their livestock production systems meeting niche market demands at a premium price. Animals that require therapeutic antibiotic treatment are removed from the “antibiotic-free” population and marketed in the normal stream

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21
Q

what happens if animals are treated by antibiotics

A

Treated animals do not enter the food chain until the withdrawal period for the antibiotic used has been completed

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22
Q

why don’t all places do antibiotic-free practices

A

Potential and actual health problems encountered by antibiotic-free producers limit the number of producers willing to adopt this practice

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23
Q

how many broiler operations in North America are antibiotic-free? how do producers successfully carry this out

A

Currently, almost half of the broiler industry in North America is antibiotic-free; this is facilitated by very stringent biosecurity measures that seriously limit exposure to pathogens

24
Q

for a farmer who uses antibiotics how can they use them better

A

Wiser use of antibiotics in human and animal medicine may retard the rate of the development of antibiotic resistance and alternative pathways for preventing bacterial disease can be valuable tools in this endeavor.

25
Q

what are growth-promoting hormones

A

growth-promoting hormones and feed additives are used in some livestock sectors to increase production efficiency

26
Q

what kind of operations are growth-promoting hormones and feed additives used in

A

Hormones are used only in beef operations; various types of feed additives may be utilized in all animal, poultry, and aquaculture operations

27
Q

what is the purpose of food additives what is it comparable to in human diets

A

The feed additives used in livestock production systems are used for the same purposes as supplements that you might take to boost specific components of your diet

28
Q

when did growth-promoting hormones first start being used in Canada

A

have been used in feedlot cattle in Canada since the 1960s

29
Q

how does the use of growth-promoting hormones increase productivity

A

The use of these products confers an increase in the growth rate of 10 to more than 30%, improves the animals’ ability to utilize nutrients, increases lean meat yield and makes it more cost-effective to produce beef; savings are passed on to consumers through more affordable meat

30
Q

what hormones growth pemoters are approved in Canada and the USA and other beef-producing countries

A

Natural hormones, estradiol 17β, progesterone and testosterone along with synthetic hormones, zeranol, melengestrol acetate, and trenbolone acetate are approved for use

31
Q

how can the natural and artificial hormones given to cows

A

These hormones are administered to cattle in small slow-release implants embedded in the ears. Melengesterol acetate (MGA), another synthetic hormone, is provided to heifers as a feed additive

32
Q

what is Melengesterol acetate (MGA) used for how is it given

A

MGA increases the rate of gain, improves feed efficiency, and suppresses heat cycles. MGA is also used in estrus-synchronization protocols for breeding heifers. it is provides to heifers through feed additives

33
Q

what is Melengesterol acetate (MGA) used for how is it given

A

MGA increases the rate of gain, improves feed efficiency, and suppresses heat cycles. MGA is also used in estrus-synchronization protocols for breeding heifers. it is provided to heifers through feed additives

34
Q

are hormones used in Canada to produce eggs, milk, pork or poultry

A

no

35
Q

is there any scientific evidence that proves hormone use in feedlot cattle jeopardizes human health

A

no

36
Q

what is recombinant bovine growth hormone (rBGH), also called recombinant bovine somatotropin (rBST)

A

it can be administered to dairy cows in the United States for the purpose of increasing the efficiency of milk production. rBGH is not permitted in Canadian dairy production because of animal welfare concerns.

37
Q

are feed additives to considered additions to feed or supplying nutritional requirement

A

Feed additives may be considered as additions to feed not directly related to supplying nutritional requirements.

38
Q

why are feed additives useful

A

Feed additives are used to increase the rate of gain and feed efficiency thereby decreasing the cost of production.

39
Q

what are two common feed additives used in beef feedlots

A

Two feed additives commonly used in beef feedlots are ionophores and beta-agonists.

40
Q

can feed additives be used as an alternative to antibiotics

A

yes

41
Q

what are ionophores and how do they work

A

Ionophores are feed additives used in cattle diets to manipulate rumen fermentation, improve feed efficiency and control coccidiosis

42
Q

how do ionophores reduce GHG emissions

A

The altered microbial population of the rumen increases feed efficiency and decreases the production of both methane and ammonia

43
Q

how do ionophores improve animal wellbeing

A

Ionophores also reduce the risk of acidosis, coccidiosis, and bloat, benefiting the welfare of the animals. Ionophoric coccidiostats may also be given to poultry, dairy cattle, swine, sheep, and goats to control coccidiosis.

44
Q

While classified as antimicrobials, ionophores are not considered therapeutic antibiotics and are not used in human medicine what would they be best classified as

A

The ionophores act as anti-bacterial agents and would be better classified as such than as antibiotics

45
Q

how do beta Beta-adrenergic agonists additives work

A

Beta-adrenergic agonists shift nutrients away from fat deposition and towards lean muscle growth

46
Q

what two beta-agonists are used in feedlots

A

Two beta-agonists that have been used in beef feedlots are ractopamine hydrochloride and zilpaterol hydrochloride

47
Q

how are the commercially available ionophores currently classified and why

A

The commercially available approved ionophores (monensin, lasalocid and salinomycin) are classified as antimicrobials because they negatively affect gram-positive bacteria and protozoa in the rumen

48
Q

when in production are beta-agonists added to feed

A

Beta-agonists are added to feed during the last 20 to 40 days of the finishing period, increasing final carcass weight without incurring an increase in feed intake

49
Q

can beta-agonist be added to pigs feed

A

yes, The beta-agonist ractopamine is also licensed for use in swine production; however, virtually all pork producers in Canada are now part of the Canadian Ractopamine-Free Certification program. Pork from pigs fed ractopamine cannot be exported to the European Union, Mainland China or Russia.

50
Q

can you use beta-agonist in any animal

A

no the Use of beta-agonists in other species, such as sheep and goats, is illegal and the use of beta-agonists not approved for a specific livestock species is also illegal.

51
Q

can beta-agonist be used for humans and animals

A

Beta-agonists are widely used in human medicine and none of the products approved for humans can be used in livestock. Clenbuterol is a beta-agonist used to treat pulmonary disorder in horses; its use as a growth promotant in other livestock is also illegal.

52
Q

how do Hormones and growth-promoting feed additives are utilized to increase production efficiency and reduce costs to producers and consumers

A

The increased production efficiency also decreases the number of animals required for meat production and decreases the amount of time they spend on feed, thus reducing their environmental impact.

53
Q

what thing must be considered to make sure additives and hormone don’t negatively impact anything

A

It is important that these products be safe for consumers and that they are perceived as being safe and that their use does not impinge on the welfare of the animals.

54
Q

where are hormone growth promoters banned

A

the EU

55
Q

What canges were implamented by the canadian food inspection agency and health in 2018 for antimicrobials

A

Changes implemented by the Canadian Food Inspection Agency and Health Canada in 2018 also moved 340 over-the-counter (OTC) antimicrobials to a by-prescription-only status