Listeria Flashcards

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1
Q

What bacteria is Listeria related to and how are they different?

A

Bacillus but it doesn’t form spores

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2
Q

How many species does Listeria have?

A

6 but only one pathogen

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3
Q

What species of Listeria causes CNS infections and abortions in ruminants?

A

Listeria monocytogenes

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4
Q

What does Listeria look like on gram stain?

A

gram positive, small, fat rod, but commonly coccoid

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5
Q

What do colonies of Listeria monocytogenes look like?

A

relatively small colonies with narrow zone beta hemolysis

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6
Q

Is Listeria monocytogenes catalase positive or negative?

A

positive

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7
Q

Where does L. monocytogenes live?

A

in soil, plant material, and intestinal tracts especially of herbivores

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8
Q

At what pH does Listeria multiply?

A

pH 5.5 to 9.0

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9
Q

What pH does silage need to be below to prevent Listeria?

A

5

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10
Q

What is human listeriosis commonly due to?

A

food contamination: raw hotdogs, ice cream, milk, cheeses, organically grown lettuce

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11
Q

What kills Listeria in food?

A

proper pasteurization

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12
Q

What toxin does Listeria have?

A

listeriolysin O

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13
Q

What type of toxin is listeriolysin O?

A

cholesterol-binding

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14
Q

What is the function of listeriolysin O?

A

it destroys the phagosomal membrane and allows listeria to be a facultative intracellular parasite

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15
Q

How does infection of Listeria usually happen?

A

most animals and humans are exposed to Listeria but become infected due to bad silage or severely contaminated foods

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16
Q

What hosts are especially susceptible to Listeria?

A

immunosuppresed - pregnancy, stresses, and intercurrent diseases

17
Q

What disease does Listeria cause in ruminants?

A

circling disease and abortions

18
Q

What are the symptoms of circling disease?

A

meningoencephalitis, unilateral facial paralysis, fever, blindness, head pressing, and circling in the same direction

19
Q

What does listeriosis cause?

A

septicemia in monogastrics and young ruminants

20
Q

What immunization is possible for Listeria?

A

a live-attenuated vaccine (not available in US) that expresses cancer antigens

21
Q

What treatment works for Listeria?

A

ampicillin, penicillin, and tetracycline