How Nerves Work 3 Flashcards
Graded Potentials + Synaptic Integration
<p>What is a ligand?</p>
<p>A substance that forms a complex with a biomolecule</p>
<p>What are some examples of graded potentials?</p>
<p>Generator potential (at sensory receptor)</p>
<p>Postsynaptic potential (at synapses)</p>
<p>Endplate potential (at neuromuscular junction)</p>
<p>Pacemaker potential (in pacemaker tissue)</p>
<p>What is the job of the graded potential?</p>
<p>To get the cell to threshold and fire an action potential</p>
<p>How are graded potentials decremental?</p>
<p>They don't trevel very well along membranes</p>
<p>What does decremental mean?</p>
<p>Process of gradually becoming less</p>
<p>Why are graded potentials decremental?</p>
<p>The current flows out of the graded potential as it travels along the axon</p>
<p>What distance can graded potentials travel?</p>
<p>Only short due to being decremental</p>
<p>How are graded potentials graded?</p>
<p>They may be of a higher intensity or a lower intensity</p>
<p>What is the size of the graded potential proportional to?</p>
<p>The size of the stimuli</p>
Show how graded potentials can be polarising or depolarising on a graph?
<p>What is the threshold for opening Na+gated channels and firing an action potential?</p>
<p>-55mV</p>
<p>What is an excitatiry post synaptic potential (EPSP)?</p>
<p>Anything that takes the potential towards threshold</p>
<p>What is an inhibitory post synaptic potential (IPSP)?</p>
<p>Anything that takes the potential away from threshold</p>
<p>What happens once a graded potential reaches threshold?</p>
<p>An action potential is fired</p>
<p>How does a channel being part of the receptor affect the response?</p>
<p>Channel/receptor combinations produce a faster response, whereas if the channel uses a seperate receptor it produces a slower response</p>
<p>What channels produce an IPSP response?</p>
<p>Cl-(fast)</p>
<p>K+(slow)</p>
<p>Do Cl-channels produce a fast or slow response?</p>
<p>Fast</p>
<p>Do K+channels produce a fast or slow response?</p>
<p>Slow</p>
<p>What channels produce an EPSP?</p>
<p>Na+(fast, also permeable to K+due to them both having a charge of +1)</p>
<p>Closing leaky K+(slow)</p>
<p>Do Na+channels produce a fast or slow response?</p>
<p>Fast</p>
<p>Does closing leaky K+channels create a fast or slow response?</p>
<p>Slow</p>
<p>What are presynaptic potentials generated by?</p>
<p>Neurotransmitter opening or closing ion channels</p>
<p>Are graded potentials generated by ligand or voltage gated channels?</p>
<p>Ligand</p>
<p>Are action potentials generated by voltage or ligand gated channels?</p>
<p>Voltage</p>
What is synaptic integration?
The summation of graded potentials to reach threshold
Why are graded potentials generated next to the axon (where the axon potential is generated) more likely to reach threshold than one further away?
Graded potentials are decrimental
What is temporal summation?
Stimulating the same potential one after an other
What is spatial summation?
Stimulating two potentials at the same time
What kinds of synapses can summate?
Both inhibatory and excitatory
Where do synapses that are IPSP tend to be located?
On the soma