How Nerves Work 3 Flashcards

Graded Potentials + Synaptic Integration

1
Q

<p>What is a ligand?</p>

A

<p>A substance that forms a complex with a biomolecule</p>

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2
Q

<p>What are some examples of graded potentials?</p>

A

<p>Generator potential (at sensory receptor)</p>

<p>Postsynaptic potential (at synapses)</p>

<p>Endplate potential (at neuromuscular junction)</p>

<p>Pacemaker potential (in pacemaker tissue)</p>

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3
Q

<p>What is the job of the graded potential?</p>

A

<p>To get the cell to threshold and fire an action potential</p>

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4
Q

<p>How are graded potentials decremental?</p>

A

<p>They don't trevel very well along membranes</p>

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5
Q

<p>What does decremental mean?</p>

A

<p>Process of gradually becoming less</p>

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6
Q

<p>Why are graded potentials decremental?</p>

A

<p>The current flows out of the graded potential as it travels along the axon</p>

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7
Q

<p>What distance can graded potentials travel?</p>

A

<p>Only short due to being decremental</p>

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8
Q

<p>How are graded potentials graded?</p>

A

<p>They may be of a higher intensity or a lower intensity</p>

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9
Q

<p>What is the size of the graded potential proportional to?</p>

A

<p>The size of the stimuli</p>

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10
Q

Show how graded potentials can be polarising or depolarising on a graph?

A
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11
Q

<p>What is the threshold for opening Na+gated channels and firing an action potential?</p>

A

<p>-55mV</p>

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12
Q

<p>What is an excitatiry post synaptic potential (EPSP)?</p>

A

<p>Anything that takes the potential towards threshold</p>

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13
Q

<p>What is an inhibitory post synaptic potential (IPSP)?</p>

A

<p>Anything that takes the potential away from threshold</p>

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14
Q

<p>What happens once a graded potential reaches threshold?</p>

A

<p>An action potential is fired</p>

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15
Q

<p>How does a channel being part of the receptor affect the response?</p>

A

<p>Channel/receptor combinations produce a faster response, whereas if the channel uses a seperate receptor it produces a slower response</p>

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16
Q

<p>What channels produce an IPSP response?</p>

A

<p>Cl-(fast)</p>

<p>K+(slow)</p>

17
Q

<p>Do Cl-channels produce a fast or slow response?</p>

A

<p>Fast</p>

18
Q

<p>Do K+channels produce a fast or slow response?</p>

A

<p>Slow</p>

19
Q

<p>What channels produce an EPSP?</p>

A

<p>Na+(fast, also permeable to K+due to them both having a charge of +1)</p>

<p>Closing leaky K+(slow)</p>

20
Q

<p>Do Na+channels produce a fast or slow response?</p>

A

<p>Fast</p>

21
Q

<p>Does closing leaky K+channels create a fast or slow response?</p>

A

<p>Slow</p>

22
Q

<p>What are presynaptic potentials generated by?</p>

A

<p>Neurotransmitter opening or closing ion channels</p>

23
Q

<p>Are graded potentials generated by ligand or voltage gated channels?</p>

A

<p>Ligand</p>

24
Q

<p>Are action potentials generated by voltage or ligand gated channels?</p>

A

<p>Voltage</p>

25
Q

<p>What is synaptic integration?</p>

A

<p>The summation of graded potentials to reach threshold</p>

26
Q

<p>Why are graded potentials generated next to the axon (where the axon potential is generated) more likely to reach threshold than one further away?</p>

A

<p>Graded potentials are decrimental</p>

27
Q

<p>What is temporal summation?</p>

A

<p>Stimulating the same potential one after an other</p>

28
Q

<p>What is spatial summation?</p>

A

<p>Stimulating two potentials at the same time</p>

29
Q

<p>What kinds of synapses can summate?</p>

A

<p>Both inhibatory and excitatory</p>

30
Q

<p>Where do synapses that are IPSP tend to be located?</p>

A

<p>On the soma</p>