How Nerves Work 3 Flashcards
Graded Potentials + Synaptic Integration
<p>What is a ligand?</p>
<p>A substance that forms a complex with a biomolecule</p>
<p>What are some examples of graded potentials?</p>
<p>Generator potential (at sensory receptor)</p>
<p>Postsynaptic potential (at synapses)</p>
<p>Endplate potential (at neuromuscular junction)</p>
<p>Pacemaker potential (in pacemaker tissue)</p>
<p>What is the job of the graded potential?</p>
<p>To get the cell to threshold and fire an action potential</p>
<p>How are graded potentials decremental?</p>
<p>They don't trevel very well along membranes</p>
<p>What does decremental mean?</p>
<p>Process of gradually becoming less</p>
<p>Why are graded potentials decremental?</p>
<p>The current flows out of the graded potential as it travels along the axon</p>
<p>What distance can graded potentials travel?</p>
<p>Only short due to being decremental</p>
<p>How are graded potentials graded?</p>
<p>They may be of a higher intensity or a lower intensity</p>
<p>What is the size of the graded potential proportional to?</p>
<p>The size of the stimuli</p>
Show how graded potentials can be polarising or depolarising on a graph?
<p>What is the threshold for opening Na+gated channels and firing an action potential?</p>
<p>-55mV</p>
<p>What is an excitatiry post synaptic potential (EPSP)?</p>
<p>Anything that takes the potential towards threshold</p>
<p>What is an inhibitory post synaptic potential (IPSP)?</p>
<p>Anything that takes the potential away from threshold</p>
<p>What happens once a graded potential reaches threshold?</p>
<p>An action potential is fired</p>
<p>How does a channel being part of the receptor affect the response?</p>
<p>Channel/receptor combinations produce a faster response, whereas if the channel uses a seperate receptor it produces a slower response</p>
<p>What channels produce an IPSP response?</p>
<p>Cl-(fast)</p>
<p>K+(slow)</p>
<p>Do Cl-channels produce a fast or slow response?</p>
<p>Fast</p>
<p>Do K+channels produce a fast or slow response?</p>
<p>Slow</p>
<p>What channels produce an EPSP?</p>
<p>Na+(fast, also permeable to K+due to them both having a charge of +1)</p>
<p>Closing leaky K+(slow)</p>
<p>Do Na+channels produce a fast or slow response?</p>
<p>Fast</p>
<p>Does closing leaky K+channels create a fast or slow response?</p>
<p>Slow</p>
<p>What are presynaptic potentials generated by?</p>
<p>Neurotransmitter opening or closing ion channels</p>
<p>Are graded potentials generated by ligand or voltage gated channels?</p>
<p>Ligand</p>
<p>Are action potentials generated by voltage or ligand gated channels?</p>
<p>Voltage</p>
<p>What is synaptic integration?</p>
<p>The summation of graded potentials to reach threshold</p>
<p>Why are graded potentials generated next to the axon (where the axon potential is generated) more likely to reach threshold than one further away?</p>
<p>Graded potentials are decrimental</p>
<p>What is temporal summation?</p>
<p>Stimulating the same potential one after an other</p>
<p>What is spatial summation?</p>
<p>Stimulating two potentials at the same time</p>
<p>What kinds of synapses can summate?</p>
<p>Both inhibatory and excitatory</p>
<p>Where do synapses that are IPSP tend to be located?</p>
<p>On the soma</p>