DAT Endocrine System Cheat Sheet Flashcards
targets a distant cell
through the bloodstream
endocrine
secretes enzymes into
ducts
exocrine
target nearby cell
paracrine
targets itself
autocrine
Bind to surface cell membrane receptor → Receptors start cell signaling pathways via secondary messengers
peptide hormones
where do peptide hormones bind to
surface cell membrane receptors
Diffuse plasma membrane and bind receptor in cytoplasm → hormone + receptor is transported into nucleus to act
transcriptionally
steroids
after steroids diffuse thru membrane, where is receptor bound
in cytoplams
after hormone and receptor is bound, where is it transported (steroids)
nucleous
Lipid-soluble, bind to receptors in nucleus, and require protein carrier in blood
thyroid hormones
what do thyroid hormones require
protein carriers in blood
are thyroid hormones lipid soluable
yes
Water-soluble, bind receptors on target tissue, and mainly act via secondary messenger cAMP
Catecholamines:
where do catecholamines bind receptors
target tissue
what secondary messenger does catecholamines act by
cAMP
Small molecules that pass along signals (such as growth
factors and protein hormones)
secondary messengers
secondary messengers are Initiated by
ligand-receptor binding
examples of secondary messengers
Examples: IP3, cAMP, Calcium, DAG
Hypothalamus secretes releasing hormones to the…
anterior pituitary gland
what happens when apg receives hormones
it releases its own
Hypothalamus secretes…
ADH and oxytocin
where is ADH and oxytocin stored
posterior pituitary
Secreted by Alpha cells,
released when energy
levels are low
glucagen
↑ glucose levels in blood
glucagen
Stimulates liver to
convert glycogen to
glucose
glucagen
glucogen Stimulates WHAT
in liver
gluconeogenesis
Converts stored adipose
tissue into blood lipids
glucagen
Secreted by Beta cells
insulin
Anabolic, released when energy
levels are high
insulin
↓ glucose levels in blood
insulin
Stimulates liver & muscle to store
glucose as glycogen
insulin
Secreted by Delta cells
Somatostatin
Inhibits release of insulin &
glucagon
somatostatin
↑ nutrient absorption time by ↓
digestive system flow
somatostatin
Tropic hormones – Stimulate other…
endocrine glands
Stimulates adrenal cortex → releases glucocorticoids
acth
Stimulates thyroid gland to release thyroid hormones
tsh
Stimulates corpus luteum formation females
lh
Stimulates interstitial cells of testes to produce testosterone
lh
Stimulates maturation of ovarian follicles to secrete estrogen
fsh
Stimulates seminiferous tubule maturation & sperm production
fsh
Nontropic hormones – Directly
stimulate
target organs
Stimulates bone & muscle
growth
GH
Stimulates milk
production
prolactin
Does not synthesize hormones
posterior pituitary
Stores ADH & oxytocin for release
posterior pituitary
Increases
reabsorption of water by increasing
permeability of nephron’s collecting duct
ADH (vasopressin)
Increases strength of uterine
contractions; stimulates milk ejection;
induces maternal behavior
oxytocin
Secretes melatonin
pineal gland
Regulates circadian rhythm
(sleep)
pineal gland
Immune function
thymus
Secretes thymosins that
stimulate white blood cells to
become T-cells
thymus
Antagonistic to the function of
calcitonin
pth
Stimulating osteoclasts to
breakdown bone
pth
Increasing kidney
reabsorption of calcium
pth
Increasing calcium uptake
from the gut
pth
Increases spermatogenesis, secondary sex characteristics
testosterone
Menstrual cycle regulation, secondary sex characteristics
estrogen
Menstrual cycle regulation, pregnancy
progesterone
↑ basal metabolic rate in body
Thyroxine (T4) & Triiodothyronine (T3)
Calcitonin *
Stimulates osteoblast activity (builds up
bone by using calcium in the blood)
what is necessary to synthesize thyroid hormones
iodine
Converts glycogen to
glucose [↑ blood
glucose]
Epinephrine &
Norepinephrine
Vasoconstrictor to
kidneys and bladder
epinephrin and norepinephrin
Raise blood glucose levels
glucocordicoids
Degrades adipose tissue to use as
energy
glucocordicoids
↑ reabsorption of Na+ and
excretion of K+ in kidneys
Mineralocorticoids (aldosterone)
hormones involved with pancreas
glucagon, insulin, somatostatin
2 types of hormones in anterior pituitary
tropic and non tropic hormones
hormones involved in posterior pituitary
ADH and oxytocin
ACTH, LH, Tsh, FSh, what kinda hormone and where
tropic, anterior pituitary
gh, prolactin what kinda hormone and where
non tropic, posterior pituitary
t3 and t4 calcintonin where do they come from
thyroid
2 parts of hypothalamus
anterior and posterior pituitary