CVPR Week 9: Renal tubule disorders Flashcards

1
Q

Objectives

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2
Q

What’s the diagnosis?

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3
Q

Tubular function! Yay!

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4
Q

What do the renal tubules do?

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5
Q

Hormones affecting salt and water in the renal tubules

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6
Q

How do tubulopathy presents in several ways

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7
Q

Tubulopathy syndromes

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8
Q

What is renal tubular acidosis

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9
Q

Types of RTA

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10
Q

What is RTA

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Renal tubular acidosis

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11
Q

Describe normal HCO3- and H+ management

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12
Q

Features of proximal RTA

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13
Q

Describe proximal RTA and HCO3- and H+ management

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14
Q

Distal RTA type 1

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15
Q

Describe distal RTA and HCO3- and H+ management

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16
Q

How to diagnose RTA?

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17
Q

Proximal RTA Urine pH

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18
Q

Distal RTA Urine pH

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19
Q

Urine anion Gap and RTA type

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20
Q

Chronic acidosis leads to?

A

polyuria, failure to thrive and growth delay

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21
Q

Chronic hypokalemia causes

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22
Q

Calciuria in distal RTA leads to?

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23
Q

RTA has associations with?

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24
Q

Management of RTA

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25
Q

Classification of RTA

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26
Q

RTA diagnosis cheat sheet

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27
Q

Question

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28
Q

Abnormalities of water balance

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29
Q

Volume first?

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30
Q

Diabetes insipidus pathophysiology

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31
Q

Diabetes insipidus symptoms

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32
Q

Diabetes insipidus labs

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33
Q

Describe the normal response to dehydration

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34
Q

Describe the response to dehydration with diabetes insipidus

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35
Q

diabetes insipidus Dx test

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36
Q

diabetes insipidus causes

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pituitary or kidney damage, drugs, etc

37
Q

diabetes insipidus urine output

A

High urine output

38
Q

diabetes insipidus urine osmolality

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low urine osmolality

39
Q

diabetes insipidus serum osmolality

A

High serum osmolality

40
Q

SIADH AKA

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Syndrome of inappropriate anti-diuretic hormone

41
Q

SIADH description

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42
Q

SIADH blood

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low sodium and low osmolality (too much water)

43
Q

SIADH urine

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Low volume and high osmolality (too little water)

44
Q

SIADH causes

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drugs, neurologic dis., surgery, infections, pain, etc.

45
Q

What happens in SIADH?

A
46
Q

What is primary polydipsia?

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47
Q

primary polydipsia blood

A

low sodium and low osmolality (too much water)

48
Q

primary polydipsia urine

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high volume and low osmolality (too much water)

49
Q

primary polydipsia causes

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  • alcoholism
  • psychiatric disorders
  • athletes
  • excessive IV fluids
50
Q

differentiating water disorders

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51
Q

Question

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52
Q

MEtabolic alkalosis and hyperkalemia

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53
Q

Bartter’s syndrome

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54
Q

Gitelman’s syndrome

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55
Q

hypokalemia and alkalosis + hypertension

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56
Q

Liddle’s syndrome

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57
Q

Hypokalemic alkalosis

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58
Q

Most common cause of hypokalemic alkalosis?

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59
Q

Self-induced metabolic alkalosis

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60
Q

Question

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61
Q

If unexplained Acid-base?

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62
Q

What’s the diagnosis?

A