CVPR First Aid: Kidney stones Flashcards
Basic types of kidney stones
4 listed
Calcium
Ammonium magnesium phosphate
Uric acid
Cystine
Complications of Kidney stones
Can lead to severe complications such as hydronephrosis, pyelonephritis
Presentation of obstructed kidney stone
Obstructed stone presents with unilateral flak tenderness, colicky pain radiating to groin, hematuria
Kidney stone treatment and prevention
Encouraging fluid intake
What is the most commmon kidney stone presentation
Calcium oxalate stone in patient with hypercalciuria and normocalcemia
Calcium stone precipitates with?
Calcium oxalate citraturia
Calcium stone X-ray findings
Radiopaque
Calcium stone CT findings
Radiopaque
Calcium stone Urine crystal
Shaped like an envelope or dumbbell
Calcium stone prevalence
Calcium stones most common (80% of kidney stones)
Types of calcium stones
Calcium oxalate
Calcium phosphate
What type of calcium stone is most common?
Calcium oxalate
Calcium kidney stones associations
Hypocitraturia often associated with ↓ in urine pH
Causes of calcium kidney stone
Can result from:
ethylene glycol (antifreeze) ingestion
Vitamin C abuse
Hypocitraturia
Malabsorbtion (Crohn’s Disease)
Treatment of calcium kidney stone
3 listed
Thiazides
Citrate
Low-sodium diet
Calcium phosphate precipitates with
↑ pH
Calcium phosphate kidney stone X-ray findings
Radiopaque
Calcium phosphate kidney stone CT findings
Radiopaque
Calcium phosphate kidney stone urine crystal
Wedge shaped prism 582
Calcium phosphate kidney stone treatment
low-sodium diet, thiazides
Ammonium magnesium phosphate kidney stone precipitates with
↑ pH
Ammonium magnesium phosphate kidney stone X-ray findings
Radiopaque
Ammonium magnesium phosphate kidney stone CT findings
Radiopaque
Ammonium magnesium phosphate kidney stone urine crystal
Coffin lid
Ammonium magnesium phosphate kidney stone AKA
Struvite
Ammonium magnesium phosphate kidney stone prevalence
15% of kidney stones
Causes of Ammonium magnesium phosphate kidney stone
Caused by infection with urease (+) bugs (eg, proteus mirabilis, staphylococcus saprphyticus, Klebsiella) that hydrolize urea to ammonia → urine alkalinization
Ammonium magnesium phosphate kidney stone special features
Often formm staghorn caliculi
Treatment of ammonium magnesium phosphate kidney stone
Eradication of underlying infection
Surgical removal of stone
Cystine kidney stone precipitates with
↓pH
Cystine kidney stone X-ray findings
Faintly radiopaque
CT findings Cystine kidney stone
Moderately radiopaque
Cystine kidney stone urine crystal
Hexagonal
“Sixtine stones have six sides”
Causes of Cystine kidney stone
Hereditary (autosomal recessive) condition in which Cysteine-reabsorbing PCT transporter loses function, causing cytinuria
Transporter defect also results in poor reabsorption of Ornithine, Lysine, Arginine (COLA)
Cysteine is poorly soluble so stones formm in the urine
Cystine kidney stone onset
Typically begins in childhood
Cystine kidney stone special features
Can form staghorn caliculi
Cystine kidney stone special test
Sodium cyanide nitroprusside test (+)
Treatment of Cystine kidney stone
Low sodium diet
Alkalinization of urine
Chelating agents if refractory
Uric acid kidney stones precipitate with?
↓pH
Uric acid kidney stones X-ray findings
radiolUcent
Uric acid kidney stones CT findings
Minimally visible
Uric acid kidney stones urine crystal
Rhomboid or rosettes
Uric acid kidney stones prevalence
≈5% of all stones
Risk factors for Uric acid kidney stones
↓ urine volume
Arid climates
Acidic pH
Uric acid kidney stones are associated with?
Strong association with hyperuricemia (eg, gout)
Often seen in disease with high cell turnover (eg, leukemia)
Treatment of Uric acid kidney stones
Alkalization of urine
Allopurinol
Pictures of urine crystals
582
What is hydronephrosis
Distention/dilation of renal pelvis and calyces
Dilation occurs proximal to the site of pathology
Causes of hydronephrosis
Usually caused by urinary tract obstruction (eg, renal stones, severe BPH, congenital obstructions, cervical cancer, injury to uterer)
Other causes include;
retroperitoneal fibrosis
Vesicoureteral reflux
Signs of hydronephrosis
Creatinine becomes elevated if obstruction is bilateral or if patient has an obstructed solitary kidney
Leads to compression and possible atrophy of renal cortex and medulla
What is the most common renal malignancy?
Renal cell carcinoma
Renal cell carcinoma most commonly occurs in?
Men 50-70
↑incidence with smoking and obesity