Cardiovascular anatomy 2 Flashcards
Wall tension equation
Wall tension = pressure x radius
Wall stress equation
Wall stress = pressure x radius / 2x wall thickness
Ejection fraction equation
EF = SV / EDV = (EDV - ESV) / EDV
What is LV ejection fraction an index of?
Left ventricular ejection fraction is an index of ventricular contractility
EF AKA
Ejection Fraction
EF in systolic HF
EF is decreased in systolic HF However, EF is normal in HF with preserved ejection fraction
Starling’s law
Force of contraction is proportional to end-diastolic length of cardiac muscle fiber (preload) The law states that the stroke volume of the heart increases in response to an increase in the volume of blood in the ventricles, before contraction (the end diastolic volume), when all other factors remain constant.
Factors that Increase contractility
Catecholeamines Positive ionotropes (e.g. digoxin)
Factors that decrease contractility
Loss of myocardium (e.g. MI) B-blockers (acutely) Non-dihydropyridine Ca channel blockers Dilated cardiomyopathy
Resistance equation
R = ΔP/Q = 8η x L / πr4
Flow equation
Q = ΔP/R
Pressure equation
ΔP = Q x R
Volumetric flow rate equation
Q = flow velocity (v) x cross-sectional area (A)
Resistance in series
R = R1 + R2 + R3 •••
Resistance in parallel
R = 1/R1 + 1/R2 + 1/R3•••
What vessels have the highest cross-sectional area?
Capillaries
What vessels have the lowest flow velocity?
Capillaries
How does the pressure gradient determine flow?
The pressure gradient drives flow from high to low pressure
What vessels have the account for the highest TPR?
Arterioles account for most of the TPR
What vessels contain the most blood volume?
Veins provide most of the blood storage capacity