CVPR Week 5: Gas Transport I

Question 1

Objectives

Answer 1

Question 2

Gas exchange procedure

5 listed

Answer 2

1. Atmosphere to alveoli
2. Alveoli to pulmonary capillary
3. Pulmonary capillaries to tissues
4. tissue extraction
5. CO₂ transfer

Question 3

Explain the process of gas exchange

Answer 3

1. Atmosphere to alveoli
2. Alveoli to pulmonary capillary
3. Pulmonary capillaries to tissues
4. tissue extraction
5. CO2 transfer

Question 4

The P_O2 depends on?

Answer 4

Barometric pressure P_B

Question 5

Daltons law of partial pressures

Answer 5

Total pressure = summation of partial pressures

Question 6

Atmospheric P_O2 vs inspired P_O2

Answer 6

Question 7

Tracheobronchial tree structural description

Answer 7

Question 8

Tracheobronchial tree zones

Answer 8

Question 9

Cross-sectional area in different portions of the lung

Answer 9

Question 10

Surface area of the respiratory bronchiols

Answer 10

~140 m²

Question 11

speed of flow in the respiratory bronchioles

Answer 11

V = Q / A

Question 12

From the atmosphere to alveoli

Answer 12

Question 13

What are these?

Answer 13

Alveoli

Question 14

Factors affecting diffusion in the alveoli

3 listed

Answer 14

Question 15

Fick’s Law of diffusion

Answer 15

Question 16

How is O₂ carried in the blood?

2 listed

Answer 16

Dissolved and bound to Hb

Question 17

Typically, how much blood is transported in either state?

Answer 17

Question 18

Alveoli to pulmonary capillaries

Answer 18

Question 19

Movement of O2 between alveolar gas and pulmonary capillary blood is determined by?

Answer 19

Fick’s law of diffusion

Question 20

Diffusion is impaired by?

Answer 20

thickened barrier (such as in pulmonary fibrosis) or a reduced driving pressure (↓ alveolar PO2 at altitude or COPD)

Question 21

How is diffusion impaired by pulmonary fibrosis?

Answer 21

Thickened barrier

Question 22

how does a reduced PO2 impair diffusion

Answer 22

reduced driving pressure

Question 23

How does COPD impair diffusion?

Answer 23

Reduced driving pressure

Question 24

O₂ content is defined by?

Answer 24

the total amount of O₂ carried in the blood (Dissolved + HbO₂)

Question 25

The majority of O₂ carried in the blood is?

Answer 25

bound to Hb (HbO₂)