CVPR Week 3: Pressure Volume Loops Flashcards

1
Q

Objectives

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2
Q

What is a pressure volume loop?

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3
Q

The value of pressure-volume loops

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4
Q

Question 1

A

A.

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5
Q

Question 2

A

C.

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6
Q

Question 3

A

B.

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7
Q

Question 4

A

B

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8
Q

What is this?

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9
Q

How to create a pressure-volume loop?

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10
Q
  • What happens between 1 and 2?
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11
Q

What happens between 2 and 3?

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12
Q

What happens between 3 and 4?

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13
Q

What happens between 4 and 1?

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14
Q

What is stroke volume =

A

end diastolic volume - end systolic volume = SV

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15
Q

What is the stroke volume?

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16
Q

What is the ejection fraction?

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17
Q

What does the whole shaded area represent?

A

ventricular stroke work

Work = Force x Distance

Work = Pressure x Volume

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18
Q

Describe Starling’s Law of the heart

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19
Q

What is preload?

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20
Q

Preload equation

A

P(r)/2w

r = radius of sphere

w = wall thickness

preload directly proportional to pressure

Preload directly proportional to volume

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21
Q

End-diastolic pressure volume relationship

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22
Q

End-diastolic pressure volume relationship on a pressure volume loop

A
23
Q

What is afterload?

A
24
Q

Afterload equation

A

P(r)/2w

25
Q

Afterload is directly proportional to?

A

Pressure

or

to simplify further

Afterload is proportional to systemic systolic blood pressure

26
Q

Preload proportionality

A
  • preload is directly proportional to volume
  • preload is directly proportional to pressure
27
Q

What point on a pressure-volume loop represents maximal ventricular contraction

A

point 3

28
Q

Identify

A
29
Q

End-systolic pressure volume relationship

A
30
Q

ESPVR and Contractility

A
31
Q

Review of preload, afterload and contractility?

A
32
Q

ESPVR AKA

A

End-systolic pressure volume relationship

33
Q

EDPVR AKA

A

End-diastolic pressure-volume relationship

34
Q

Changing parameters: Increase preload

A
35
Q

Changing parameters: Decrease preload

A
36
Q

Changing parameters: Increase afterload

A
37
Q

Changing parameters: Decrease afterload

A
38
Q

Changing parameters: Increase contractility

A
39
Q

Changing parameters: Decrease contractility

A
40
Q

Pressure-volume loop: Systolic heart failure

A

systolic heart failure

41
Q

Pressure-volume loop: Diastolic heart failure

A
42
Q

Inotropy definition and examples

A
  • An inotrope is an agent that alters the force or energy of muscular contractions.
  • Negatively inotropic agents weaken the force of muscular contractions.
  • Positively inotropic agents increase the strength of muscular contraction.
43
Q

Post spinal hypotension treatment

A
44
Q

An increase in contractility does what to the ESPVR?

A

steepens it

45
Q

An decrease in contractility does what to the ESPVR?

A

flattens it or decreases it

46
Q

What is afterload represented by?

A

Afterload is represented by the pressure seen between 2 and 3

47
Q

How is contractility represented?

A

by the steepness of the ESPVR

48
Q

What is preload represented by?

A

how far out (to the right) on the EDPVR we go

49
Q

What is the line of contractility referring to?

A
50
Q

The slope of the ESPVR represent?

A

The slope of this line represents

(ΔP/ΔV) = End-systolic elastance

51
Q

What is End-systolic elastance?

A

End-systolic elastance = (ΔP/ΔV)

it is represented by the slope of the ESPVR

52
Q

Label the Diastolic pressure, systolic pressure, end-diastolic volume, end-systolic volume and stroke volume on a pressure-volume loop (define ejection fraction)

A
53
Q

Elastance equation

A

ΔP / ΔV