CVPR First aid: renal pathology 2 Flashcards

1
Q

Types of urinary incontinence

A

Stress incontinence

Urgency incontinence

Mixed incontinence

Overflow incontinence

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2
Q

Stress incontinence

A

Outlet incompetance (urethral hypermobility or intrinsic sphincteric deficiency) → leak with ↑ intra-abdominal pressure (eg, sneezing, lifting), ↑ risk with obesity, vaginal delivery, prostate surgery

(+) bladder stress test (directly observed leakage from urethra upon coughing or Valsalva maneuver)

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3
Q

Treatment of Stress incontinence

A

Pelvic floor muscle strengthening (Kegel exercises, weight loss, pessaries

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4
Q

Urgency incontinence

A

Overactive bladder (detrusor instability) → leak with urge to void immediately

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5
Q

Urgency incontinence associations

A

UTI

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6
Q

Treatment of Urgency incontinence

A

Kegel exercises

Bladder training (timed voiding, distraction or relaxation techniques)

Anti-muscarinics (eg, oxybutynin)

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7
Q

Mixed incontinence

A

Features of both stress and urgency incontinence

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8
Q

Overflow incontinence

A

Incomplete emptying (detrusor under activity or outlet obstruction) → leak with over-filling

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9
Q

Overflow incontinence associations

A

Polyuria (eg, diabetes)

bladder outlet obstruction (eg, BPH)

Neurogenic bladder (eg, MS)

↑ post-void residual (urinary retention on catheterization or ultrasound

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10
Q

Treatment of Overflow incontinence

A

Catheterization

Relieve obstruction (eg, α-blockers for BPH)

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11
Q

What is a urinary tract infection?

A

Inflammation of urinary bladder

Presents as suprpubic pain, dysuria, urinary frequency, urgency

Systemic signs (eg, high fever, chills) are usually absent

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12
Q

Risk Factors for UTI

A

Female

Sexual intercourse (“honeymoon cystitis”)

Indwelling catheter

Diabetes mellitus

Impaired bladder emptying

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13
Q

Causes of UTI

A

E Coli (most common)

Staphylococcus saprophyticus - seen in sexually active young women (E coli is still more common in this group)

Klebsiella

Proteus mirabilis - urine has ammonia scent

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14
Q

Lab findings of UTI

A

(+) leukocyte esterase

(+) nitrates (indicate gram (-) organisms)

Sterile Pyuria and (-) urine cultures suggest urethritis by Neisseria gonorrhoeae or Chlamydia trachomatis

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15
Q

UTI AKA

A

Urinary tract infection

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16
Q

Acute bacterial cystitis AKA

A

UTI

17
Q

Types of Pyelonephritis

A

Acute pyelonephritis

Chronic pyelonephritis

18
Q

Acute pyelonephritis

A

Neutrophils infiltrate renal interstitium

Affects cortex with relative sparing of glomeruli/vessels

19
Q

Presentation of acute pyelonephritis

A

Fevers

Flank pain (costovertebral angle tenderness

Nausea/vomiting

Chills

20
Q

Causes of acute pyelonephritis

A

Ascending UTI (E coli is most common) hematogenous spread to kidney

21
Q

Urine in acute pyelonephritis

A

WBCs in urine +/- WBC casts

22
Q

Imaging of acute pyelonephritis

A

CT shows striated parenchymal enhancement