CVPR Week 5: Occupational lung disease Flashcards
Keys to Dx Occupational lung disease
- occupational history
- supplement history by material safety data sheets (MSDS)
Occupational history: The quick survey
4 listed questions
- Where do/did you work?
- How do/did you do your job?
- Are/were you exposed to hazards?
- Co-workers or family exposed?
Rhinitis and laryngitis

Tracheitis, bronchitis and bronchiolitis

Asthma and COPD

Cancer

Interstitial disease

Large particles

Occupational airway disorders
4 listed

Occupational asthma epidemiology
2 listed

Occupational asthma definition

Types of Occupational asthma
- OA with latency
- OA without latency

Occupational asthma most common type
Occupational asthma with latency
Occupational asthma with latency
- immune sensitization
- LMW compounds or not IgE mediated
- HMW compounds or IgE mediated
Occupational asthma without latency
- Non-allergic irritant mediated
- RADS (Reactive Airways Dysfunction Syndrome)
- Chlorine and Ammonia
- RADS (Reactive Airways Dysfunction Syndrome)
Common causes of Occupational asthma
HMW compounds (high molecular weight compounds)
LMW Compounds (low molecular weight compounds)
Common causes of Occupational asthma
HMW compounds
3 listed
- Animal products
- Plant products
- Biologic enzymes
Common causes of Occupational asthma
LMW compounds
4 listed
- Isocyanates
- Anhydrides
- Wood dusts
- Metals
LMW compounds AKA
Low molecular weight compounds
HMW compounds AKA
High molecular weight compounds
Dx of Occupational asthma

Occupational asthma PFT
4 listed
- Peak flows before and after a work shift
- Spirometry before and after a work shift
- Methacholine challenge before and after a work shift
- Specific inhalation challenge test
Occupational asthma peak flows

Management for irritant-induced occupational asthma
Limit exposures
Management for sensitizer-induced occupational asthma
Removal from workplace exposures
Question


Interstitial lung disease classifications
2 listed
- Pneumoconiosis
- Granulomatous disease
Pneumoconiosis types
4 listed
- Silicosis
- Coal Workers’ Pneumoconiosis
- Asbestosis
- Uranium Workers’ Pneumoconiosis
Granulomatous diseases types
2 listed
- Chronic beryllium lung disease
- Hypersensitivity Pneumonitis
Silicosis & Progressive Massive Fibrosis Facts to know
5 listed

Silicosis Causes
7 listed
Occupational Exposures
- Mining
- Quarrying
- Tunneling
- Stone cutting
- Abrasive blasting
- Glass manufacture
- Ceramics
Silicosis pathology
Fundamental lesion is a silicotic nodule

What is this?

Silicotic nodule
Question


What is this?

Coal Workers’ Pneumoconiosis

Coal Workers’ Pneumoconiosis radiological features

What pathology?

Silicosis
Coal Workers’ Pneumoconiosis subtypes
- Simple CWP
- Caplan’s Syndrome
Simple Coal Workers’ Pneumoconiosis clinical features
3 listed
- often asymptomatic
- often normal PFT
- Abnormal gas exchange during exercise
Caplan’s Syndrome
PMF + RA
progressive massive fibrosis + Rheumatoid arthritis
CWP Risk for lung cancer
No risk for lung cancer
Asbestos-related diseases types
Parenchymal
Pleural
Parenchymal Asbestos-related diseases
3 listed
- Asbestosis
- Lung cancer
- Rounded Atelectasis
Pleural Asbestos-related diseases
4 listed
- Benign asbestos-related pleural effusion
- Pleural plaques
- Pleural thickening
- Malignant mesothelioma
Asbestos-related diseases Early-onset diseases
Benign asbestos-related pleural effusion
pleural plaques
Benign asbestos-related pleural effusion onset
Early-onset
Pleural plaques onset
Early-onset
Asbestosis onset
Late onset
Lung cancer onset
Late onset
Pleural plaques onset
Early or Late-onset
Malignant mesothelioma onset
Late-onset
Asbestos-related diseases causes
4 listed
Occupational exposures
- Mining
- Construction
- Shipyard work
- Automobil repair: brake linings
Asbestos-related Diseases Ferruginous body or Asbestos body
Ferruginous body or asbestos body: Indicates asbestos exposure but not necessarily presence of disease
What is this?

Asbestos body

Facts to know about Asbestosis

What pathology if any?


What pathology if any? And features


Hypersensitivity Pneumonitis types
3 listed
Best known examples
- Farmers’ lung (thermophilic actinomyces)
- Pigeon fanciers’ disease (Avian proteins)
- Humidifier’s lung (thermophilic actinomyces)
What is this?


Serology of Farmer’s Lung
Thermophilic actinomyces
Serology of Humidifier’s Lung
Thermophilic actinomyces
Serology of Pigeon Fancier’s Disease
Avian proteins
What pathology if any?

Hypersensitivity Pneumonitis
What is this CT depicting?

Hypersensitivity Pneumonitis
Signs of Hypersensitivity Pneumonitis
3 listed

Selected causes of occupational lung cancer

Methods to decrease occupational lung disease
4 listed
