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CVPR > CVPR Week 2: Pharmacology of Antiarrhythmic agents > Flashcards

CVPR Week 2: Pharmacology of Antiarrhythmic agents Flashcards

1
Q

Objectives

A
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2
Q

Classes of antiarrhythmic drugs

A
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3
Q

Class I antiarrhythmics groups

A

Na+ channel block

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4
Q

Class I antiarrhythmics: Group IA

A
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5
Q

Effect of Class I antiarrhythmics: Group IA

A
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6
Q

Class I antiarrhythmics: Group IA effects on AP

A
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7
Q

Procainamide side effects

A

and lupus-like syndrome

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8
Q

Torsade Du Pointe

A
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9
Q

Torsade Du Pointe is more likely in?

A
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10
Q

Procainamide side effects

A
  • torsade du pointes
  • and lupus like syndrome
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11
Q

Procainamide drug interactions

A
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12
Q

Class I antiarrhythmics: Group IA major action

A

Prolong AP duration

Dissociate with intermediate kinetics (3 sec)

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13
Q

Class I antiarrhythmics: Group IB major action

A

slightly shorten AP duration

Dissociation with rapid kinetics (<1sec)

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14
Q

Class I antiarrhythmics: Group IC major action

A
  • Minimal effect on AP duration
  • Dissociate with rapid kinetics
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15
Q

Class I antiarrhythmics: Group IB major action & agents

A
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16
Q

Lidocaine kinetics

A
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17
Q

Class I antiarrhythmics: Group IB effect on AP

A
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18
Q

Associate lidocaine with?

A

Ventricular compartment

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19
Q

Lidocaine caveat

A
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20
Q

Class I antiarrhythmics: Group IB adverse effects

A
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21
Q

Class I antiarrhythmics: Group IB drug interactions

A
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22
Q

Class I antiarrhythmics: Group IC effects on AP

A
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23
Q

Class I antiarrhythmics: Group IC agents

A
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24
Q

Class I antiarrhythmics: Group IC uses

A
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25
Class I antiarrhythmics: Group IC adverse effects
26
Class I antiarrhythmics: Group IC drug interactions
27
Class II antiarrhythmics: Major action
β-receptor blockade
28
Review of SA node action potential
29
β-receptor activation increases?
30
β-receptor activation activates?
31
Class II antiarrhythmics: Mechanism of antiarrhythmic action
32
Class II antiarrhythmics: Effects on AP
33
β-receptor blocker classification
34
β-receptor blocker Mnemonics
35
β-receptor blocker antiarrhythmic use
36
β-receptor arrhythmic common adverse effects
37
β-receptor blocker other adverse effects
38
Class II antiarrhythmics: drug interactions
39
antidote for β-receptor blocker overdose
Glucagon (isoproterenol)
40
Class IV antiarrhythmics: major actions
Ca2+ channel block
41
Class IV antiarrhythmics: SA Nodal potential
42
Class IV antiarrhythmics: mechanism of antiarrhythmic action
43
Class IV antiarrhythmics: effect on AP
44
Class IV antiarrhythmics: types of Ca2+ channel blockers
45
Class IV antiarrhythmics: uses of Ca2+ channel blockers
46
Class IV antiarrhythmics: cardiac adverse effects
47
Class IV antiarrhythmics: drug interactions
48
Class III antiarrhythmics: Major action
49
Class III antiarrhythmics: Agents
50
Class III antiarrhythmics: Amiodarone Mechanism of action
51
Class III antiarrhythmics: Amiodarone effect on AP
52
Class III antiarrhythmics: Amiodarone clinical uses
53
Class III antiarrhythmics: Amiodarone adverse effects 1
54
Class III antiarrhythmics: Amiodarone adverse effects 2
55
What causes this?
Class III antiarrhythmics: Amiodarone adverse effects
56
Class III antiarrhythmics: Drug interactions
57
antiarrhythmics Summary table
58
Miscellaneous Antiarrhythmics agents
59
Adenosine MOA K channels
60
Adenosine MOA Ca channels
61
Adenosine cardiac areas of effect
62
Adenosine effects
63
Adenosine effects on AP
64
Adenosine uses
65
Adenosine adverse effects
66
Adenosine drug interactions
67
Digoxin class
Miscellaneous antiarrhythmics
68
Digoxin MOA 1
69
Digoxin MOA 2
70
Digoxin MOA caveat
71
Digoxin toxicity
72
Digoxin drug interactions
73
Magnesium and Potassium class
74
Miscellaneous Antiarrhythmics summary

CVPR (93 decks)

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