Chp 14- Cells of Immune SYstem Flashcards
Leukocytes (WBCs) divided into 2 categories
Granulocytes (granules present) and Agranulocytes (no granules)
Granulocytes Cell Types (The phils)
Neutrophils, Basophils, Eosinophils
activated in initial stages of infection; accumulates at site of injury; quickly phagocytizes bacteria
Neutrophils
granulocyte that releases histamine, involved in inflammation and allergic responses
Basophil (in tissue, these are mast cells)
important in ridding body of parasitic worms; produce toxic proteins against multicellular parasites
eosinophils
Agranulocyte Cell Types
Monocyte, Lymphocyte, Dendritic Cells
agranulocyte that is not active while in blood, but enter into body tissue to mature into macrophages & dendritic cells
monocytes
Monocytes become
macrophages (big eaters/ phagocytic)
phagocytic cell that resides in tissues and removes microbes & damaged cells
Macrophages “big eaters”
Agranulocyte; group of leukocytes involved in adaptive immunity
Lymphocytes
3 Main Lymphocytes
T-cells (80%). B-cells (15%), NK cells (5%)
lymphocyte cells that make antibodies; turns into plasma cells & produces antibodies; involved in adaptive immunity
B cells
lymphocyte cells that mature in thymus; involved in adaptive immunity
T cells
lymphocyte cells that has ability to kill multiple types of cells; releases perforins that perforate membrane; involved in innate immunity
NK cells
Blood consists of 2 parts , ____
formed elements (cell component) and plasma (fluid component)
Three categories of blood cells
Red blood cells (erythrocytes), White Blood cells (Leukocytes), Platelets
Red blood cells & carry O2 in the blood
Erythrocytes
These cells are important to ALL host defenses
White Blood Cells (Leukocytes)
The formation and development of blood cells that originates from hemopoietic stem cells, found in bone marrow & induced by CSFs
hematopoiesis
Proteins that function as chemical messengers, allows cells to communicate
cytokines
group of cytokines that direct the development of various types of blood cells from hematopoietic stem cells
Colony Stimulating factors (CSFs)
Cytokines that induce cells to resist viral replication; they also help regulate the immune response
interferons
antigen presenting cells that engulf material & bring it to the cells of the adaptive I.S; initiate adaptive immune system; found in tissues
Dendritic cells
Programmed death of “self” cells that does not cause inflammation.
apoptosis
Membrane-bound vacuole that contains the material engulfed by a phagocyte.
phagosome
cells that engulf and digest microbes
phagocyte
Membrane-bound vacuole generated when a phagosome fuses with lysosomes
phagolysosome
arms of a phagocyte/protozoa that enclose extracellular material
pseudopods