Chap 15- Adaptive I.S, Antigens & Antibodies

Question 1

this immune system provides defense against SPECIFIC PATHOGEN/ highly specific

Answer 1

Adaptive Immune System

Question 2

first observed IMMUNITY after discovering how to make vaccines from weakened microbes

Answer 2

Louis Pasteur

Question 3

discovered antibodies could be transferred by means of blood plasma, or serum; antitoxins treating diptheria

Answer 3

von Behring/ Ehrlich

Question 4

dual nature of Adaptive immunity is demonstrated by

Answer 4

T cells (cellular immunity) and b cells (humoral immunity)

Question 5

T and B cells develop from

Answer 5

stem cells in Red Bone Marrow

Question 6

compounds that provoke a highly specific immune response; antibody generators

Answer 6

antigen

Question 7

Example of non microbial antigens

Answer 7

Pollen; Egg white; Blood cell surface molecules (A, B, AB, O, and Rh); Serum proteins from another individual or species; Surface molecules of transplanted tissues and organs

Question 8

small molecule that stimulates the production of antibody only when attached to a carrier molecule.

Answer 8

hapten

Question 9

Why is penicillin an example of a hapten?

Answer 9

Penicillin by itself is not antigenic, but when combined with host proteins may cause allergic reaction

Question 10

Two types of antigens

Answer 10

t dependent antigens, t independent antigens

Question 11

type of antigen that requires confirmation of T helper cell to become activated

Answer 11

T DEPENDENT antigen (most antigens are t cell dependent)

Question 12

can activate a B cell without confirmation from a T helper cell

Answer 12

T INDEPENDENT Antigen

Question 13

globular protein made in response to antigen; Immunoglobin (Ig)

Answer 13

antibodies

Question 14

Region of an antigen recognized by antibodies and antigen receptors on lymphocytes

Answer 14

epitope

Question 15

How do antibodies recognize antigens??

Answer 15

They interact with the epitopes on the antigen

Question 16

antibody structure consists of

Answer 16

2 heavy chains & 2 light chains

Question 17

two identical sites on antibody that bind to epitope

Answer 17

antigen binding site

Question 18

5 classes of Ig’s (immunoglobins/antibodies)

Answer 18

IgG, IgM, IgA, IgD, IgE

Question 19

type of Ig that enhance phagocytosis, neutralize toxins and viruses, protects fetus and newborn; half life of 23 days; fix complement

Answer 19

igG (Y shaped)

Question 20

Agglutinates microbes; first Ab produced in response to infection; fix complement

Answer 20

IgM

Question 21

type of Ig that Agglutinates microbes; first Ab produced in response to infection; fixes complement; 5 day half life

Answer 21

serum (blood serum)

Question 22

type of Ig that provides Mucosal protection

Answer 22

igA

Question 23

type of iG that initiates immune response ON B CELLS

Answer 23

IgD

Question 24

type of Ig On mast cells, on basophils, and in blood; allergic reactions; lysis of parasitic worms

Answer 24

IgE