Chap 20- Antifungals/Antivirals

Question 1

Antifungal medications can interfere with

Answer 1

nucleic acid, cell wall/plasma membrane synthesis, cell division

Question 2

Why are there few targets for eurkaryotic/fungal meds?

Answer 2

Bc they closely resemble humans cells

Question 3

What do most antifungals target that humans lack?

Answer 3

ergosterol

Question 4

_____ & _____ effect ergosterol and cause membranes to leak/ interfere w/ fungal plasma membrane synthesis

Answer 4

Azoles and Polyenes

Question 5

Actions of Antivirals

Answer 5

prevent viral entry; interfere w/ viral uncoating & nucelic acid synthesis

Question 6

chemicals similar to building blocks of RNA and DNA that interfere with nucleic acid synthesis

Answer 6

Nucleoside and nucleotide analogs

Question 7

used for Herpesviruses (chickenpox, cold sores)​

Answer 7

Acyclovir

Question 8

Prevent genome integration​

Answer 8

Integrase inhibitors

Question 9

Prevent assembly and release of viral particles​

Answer 9

Protease & Neuraminidase inhibitors