Chap 13- Viroids and Prions

Question 1

small single stranded RNA molecules that only effect plants and enter through wound sites

Answer 1

Viroids

Question 2

acellular infectious agent consisting only of protein that always results in spongiform encephalopathies

Answer 2

prion

Question 3

How are prions inherited/ transmissible?

Answer 3

Ingestion, Transplant, or Surgical instruments

Question 4

when cells produce normal form of neuronal protein

Answer 4

Prion Protein normal confirmation (PrPc) normal shape

Question 5

Infections prion proteins are _____

Answer 5

Prion Protein Scrapie confirmation (PrPsc) abnormal shape

Question 6

How does PrPsc change the confirmation (shape) of PrPc ?

Answer 6

PrPsc would change the folding of PrPc , converting it to PrPsc

Question 7

aggregation (clumping) of misfolded proteins

Answer 7

amyloids

Question 8

Effects of when proteins accumulate in neural tissues

Answer 8

neurons die, brains function deteriorates, holes in tissue, leads to transmissible spongiform encephalopathies appearance of brain tissue)