Chap 15- T cells and Cellular Immunity Flashcards

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1
Q

These cells combat intracellular pathogens, and cancer cells

A

T cells/ Cellular Immunity

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2
Q

T cells only react with

A

antigen presenting cells via their TCRs (T cell receptors)

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3
Q

type of immune cell that enables a (T cell) to recognize an antigen and create an immune response against the antigen

A

Antigen Presenting Cell (APCs)

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4
Q

The antigen presenting cell (APC) presents antigen in a _______-

A

MHC- Major Histocompatibility Complex

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5
Q

in order for T cell to recognize antigen

A

antigen must be presented with an MHC (major histocompatibility protein”

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6
Q

Examples of antigen presenting cells; these can present exogenous antigens to T cells

A

Dendritic cells, B cells, and macrophages

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7
Q

host cell surface proteins that present antigen to T cells

A

MHC- Major Histocompatibility Complex

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8
Q

Two types of MHC molecules used to present antigen

A

MHC class 1 and MHC class 2

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9
Q

this type of MHC presents ENDOGENOUS antigens ; (presents antigens found within the cell) (viral parts); produced by all nucleated cells

A

MHC Class 1

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10
Q

this type of MHC presents EXOGENOUS antigens (antigens that enter from outside); antigens produced by APCs

A

MHC Class 2

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11
Q

T cells that only recognize antigens presented on MHC 1

A

Cytotoxic T cells

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12
Q

T cells that only recognize antigens presented on MHC 2

A

Helper T cells

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13
Q

T cell that assist in humoral immunity/ b cell activation

A

T Helper cell

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14
Q

How does APC present antigen to T cell?

A

within a MHC

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15
Q

T cell that recognize/ destroy infected/cancer cells; can become a cytotoxic T lymphocyte

A

T cytotoxic cell

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16
Q

These T cells have the CD4 marker, which help them interact with appropriate MHC class (MHC class 2)

A

Helper T cells (CD4 cluster of differentiation)

17
Q

These T cells have the CD8 marker, which help them interact with appropriate MHC class (MHC class 1)

A

Cytotoxic T cells (CD8 cluster of differentiation)

18
Q

Why are T helper cells classified as CD4?

A

Because they bind to MHC class 2 molecules on B cells and APCs

19
Q

Why of T cytotoxic cells classified as CD8 molecules?

A

Because they bind to MHC class 1 molecules

20
Q

Type of T cells whose target cells are self carrying endogenous antigens; (mainly viral/parasitic)

A

CD8/Tcytotoxic Cells

21
Q

CD8/Cytotoxic cells can be activated to form

A

Cytotoxic T lymphocytes

22
Q

lymphocyte that releases perforins & granzymes that induce apoptosis; recognize Ag & MHC class 1

A

Cytotoxic T lymphocyte