Chap 15- T cells and Cellular Immunity

Question 1

These cells combat intracellular pathogens, and cancer cells

Answer 1

T cells/ Cellular Immunity

Question 2

T cells only react with

Answer 2

antigen presenting cells via their TCRs (T cell receptors)

Question 3

type of immune cell that enables a (T cell) to recognize an antigen and create an immune response against the antigen

Answer 3

Antigen Presenting Cell (APCs)

Question 4

The antigen presenting cell (APC) presents antigen in a _______-

Answer 4

MHC- Major Histocompatibility Complex

Question 5

in order for T cell to recognize antigen

Answer 5

antigen must be presented with an MHC (major histocompatibility protein”

Question 6

Examples of antigen presenting cells; these can present exogenous antigens to T cells

Answer 6

Dendritic cells, B cells, and macrophages

Question 7

host cell surface proteins that present antigen to T cells

Answer 7

MHC- Major Histocompatibility Complex

Question 8

Two types of MHC molecules used to present antigen

Answer 8

MHC class 1 and MHC class 2

Question 9

this type of MHC presents ENDOGENOUS antigens ; (presents antigens found within the cell) (viral parts); produced by all nucleated cells

Answer 9

MHC Class 1

Question 10

this type of MHC presents EXOGENOUS antigens (antigens that enter from outside); antigens produced by APCs

Answer 10

MHC Class 2

Question 11

T cells that only recognize antigens presented on MHC 1

Answer 11

Cytotoxic T cells

Question 12

T cells that only recognize antigens presented on MHC 2

Answer 12

Helper T cells

Question 13

T cell that assist in humoral immunity/ b cell activation

Answer 13

T Helper cell

Question 14

How does APC present antigen to T cell?

Answer 14

within a MHC

Question 15

T cell that recognize/ destroy infected/cancer cells; can become a cytotoxic T lymphocyte

Answer 15

T cytotoxic cell

Question 16

These T cells have the CD4 marker, which help them interact with appropriate MHC class (MHC class 2)

Answer 16

Helper T cells (CD4 cluster of differentiation)

Question 17

These T cells have the CD8 marker, which help them interact with appropriate MHC class (MHC class 1)

Answer 17

Cytotoxic T cells (CD8 cluster of differentiation)

Question 18

Why are T helper cells classified as CD4?

Answer 18

Because they bind to MHC class 2 molecules on B cells and APCs

Question 19

Why of T cytotoxic cells classified as CD8 molecules?

Answer 19

Because they bind to MHC class 1 molecules

Question 20

Type of T cells whose target cells are self carrying endogenous antigens; (mainly viral/parasitic)

Answer 20

CD8/Tcytotoxic Cells

Question 21

CD8/Cytotoxic cells can be activated to form

Answer 21

Cytotoxic T lymphocytes

Question 22

lymphocyte that releases perforins & granzymes that induce apoptosis; recognize Ag & MHC class 1

Answer 22

Cytotoxic T lymphocyte