Chap 15- T cells and Cellular Immunity Flashcards
These cells combat intracellular pathogens, and cancer cells
T cells/ Cellular Immunity
T cells only react with
antigen presenting cells via their TCRs (T cell receptors)
type of immune cell that enables a (T cell) to recognize an antigen and create an immune response against the antigen
Antigen Presenting Cell (APCs)
The antigen presenting cell (APC) presents antigen in a _______-
MHC- Major Histocompatibility Complex
in order for T cell to recognize antigen
antigen must be presented with an MHC (major histocompatibility protein”
Examples of antigen presenting cells; these can present exogenous antigens to T cells
Dendritic cells, B cells, and macrophages
host cell surface proteins that present antigen to T cells
MHC- Major Histocompatibility Complex
Two types of MHC molecules used to present antigen
MHC class 1 and MHC class 2
this type of MHC presents ENDOGENOUS antigens ; (presents antigens found within the cell) (viral parts); produced by all nucleated cells
MHC Class 1
this type of MHC presents EXOGENOUS antigens (antigens that enter from outside); antigens produced by APCs
MHC Class 2
T cells that only recognize antigens presented on MHC 1
Cytotoxic T cells
T cells that only recognize antigens presented on MHC 2
Helper T cells
T cell that assist in humoral immunity/ b cell activation
T Helper cell
How does APC present antigen to T cell?
within a MHC
T cell that recognize/ destroy infected/cancer cells; can become a cytotoxic T lymphocyte
T cytotoxic cell