Chapter 45 - Pharynx Flashcards

1
Q

What are the three main sections of the pharynx?

A

Nasopharynx, oropharynx, and laryngopharynx.

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2
Q

What role does the pharynx play during respiration?

A

It is a musculomembranous tubular structe not supported by bone or cartilaginous matrix and facilitates airflow and pressure changes while preventing communication between the nasopharynx and oropharynx.

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3
Q

How does the soft palate interact with the larynx during respiration?

A

During respiration,
the caudal free margin of the soft palate intimately contacts the
subepiglottic tissue at the base of the equine larynx

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4
Q

What anatomical structures are attached to the nasopharynx?

A

Pterygoid, palatine, and hyoid bones, as well as laryngeal, cricoid, and thyroid cartilages.

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5
Q

What intraluminal pressure range must the nasopharynx withstand?

A

24–50 cm H2O.

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6
Q

What is the maximum airflow velocity the nasopharynx can accommodate?

A

Up to 90 L/s.

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7
Q

Which muscles are primarily responsible for altering the size and configuration of the nasopharynx?

A

Muscles that move the tongue, insert on the hyoid apparatus and larynx, and regulate soft palate position.

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8
Q

How is the musculature of the pharynx classified?

A

Into intrinsic and extrinsic muscles.

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9
Q

What is the primary function of the intrinsic musculature in the nasopharynx?

A

To stabilize the nasopharynx through muscular contractions.

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10
Q

What structure forms the floor of the nasopharynx?

A

The soft palate.

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11
Q

What are the components of the soft palate?

A

Oral mucous membrane, palatine glands, palatine aponeurosis, palatinus and palatopharyngeus muscles, and nasopharyngeal mucous membrane.

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12
Q

How does the palatine aponeurosis contribute to the anatomy of the nasopharynx?

A

It attaches to the caudal margin of the hard palate and helps maintain structural integrity.

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13
Q

Which 4 muscles coordinate the position of the soft palate?

A

Tensor veli palatini, levator veli palatini, palatinus, and palatopharyngeus muscles.

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14
Q

What is the innervation of the tensor veli palatini muscle?

A

Mandibular branch of the trigeminal nerve.

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15
Q

Which muscle elevates the soft palate during swallowing?

A

Levator veli palatini muscle.

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16
Q

Where does the palatinus muscle originate?

A

The caudal aspect of the palatine aponeurosis.

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17
Q

What is the function of the palatopharyngeus muscle?

A

To shorten and depress the soft palate towards the tongue.

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18
Q

How does the tensor veli palatini muscle affect the nasopharynx during inspiration?

A

It tenses the soft palate and expands the nasopharynx.

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19
Q

What is the role of the stylopharyngeus muscle in the pharynx?

A

It acts as a pharyngeal dilator to maintain tension in the nasopharynx.

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20
Q

Which nerve innervates the caudal stylopharyngeus muscle?

A

Glossopharyngeal nerve.

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21
Q

How is the blood supply to the soft palate provided?

A

By the linguofacial trunk and maxillary artery.

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22
Q

What is the venous drainage pattern for the soft palate?

A

It occurs via accompanying veins.

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23
Q

Where do lymph vessels from the soft palate drain?

A

Toward the retropharyngeal lymph nodes.

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24
Q

What type of receptors provide afferent innervation to the nasopharynx?

A

Pressure, mechanical, and temperature receptors.

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25
Q

What anatomical features separate the nasopharynx from the oropharynx?

A

The soft palate.

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26
Q

Which muscle has a pulley-like effect on the soft palate?

A

Tensor veli palatini muscle.

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27
Q

What are the main components of the intrinsic musculature of the nasopharynx?

A

Muscles of the soft palate and nasopharyngeal muscles.

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28
Q

How does the hyoid apparatus influence the nasopharynx?

A

Muscles affecting the hyoid can alter the size and stability of the nasopharynx.

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29
Q

what is the anatomical relationship between the soft palate and the larynx?

A

The caudal margin of the soft palate forms the floor of the nasopharynx, surrounding the larynx.

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30
Q

How is the position of the soft palate dynamically regulated?

A

Through coordinated contractions of specific muscles during breathing and swallowing.

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31
Q

What anatomical structure extends from the base of the epiglottis to the arch of the cricoid cartilage?

A

Laryngopharynx.

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32
Q

What anatomical feature provides structural support to the nasopharynx despite the lack of bone?

A

Muscular contraction and muscle attachments to adjacent bones.

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33
Q

How do the intrinsic muscles affect the configuration of the nasopharynx?

A

They enable timely contractions that adjust tension and diameter during respiration.

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34
Q

What is the effect of the levator veli palatini muscle on the nasopharynx?

A

It elevates the soft palate, closing off the nasopharynx during swallowing.

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35
Q

Why is the role of the oropharynx gaining importance in equine pharyngeal disease?

A

Increased understanding of its anatomy and functions, particularly related to the hypoglossal nerve.

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36
Q

Which muscle fibers continue caudad from the palatine aponeurosis?

A

The palatopharyngeus muscle fibers.

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37
Q

What anatomical relationship exists between the nasopharynx and the auditory tube?

A

The levator veli palatini arises from the lateral lamina of the auditory tube.

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38
Q

How do the intrinsic and extrinsic muscles of the pharynx work together?

A

They coordinate to adjust the size and position of the nasopharynx and oropharynx during various physiological functions.

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38
Q

What is the physiological significance of the nasopharynx’s ability to withstand pressure changes?

A

It allows effective respiration during varying airflow conditions.

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39
Q
A

Figure 45-1. The extrinsic structures relevant to equine nasopharynx
stability, showing the definition of the nasopharynx and relative relationships
of the hyoid apparatus, larynx, and extrinsic muscular attachments. a,
Mandible; b, genioglossus muscle; c, geniohyoideus muscle; d, styloglossus;
e, hyoglossus muscle; f, basihyoid bone; g, hyoepiglotticus muscle.

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40
Q
A

Figure 45-2. The intrinsic structures of the nasopharynx. The nasopharynx forms the passageway that transfers airflow from the caudal aspect of the nasal cavity to the larynx. The floor of the nasopharynx is formed by the soft palate and its relevant structures (a, Palatine aponeurosis; b, oral mucosa; c, glandular layer; d, palatinus muscle) and is normally in a subepiglottic position during respiration. The hamulus (f) of the pterygoid bone, and the tensor veli palatini (e), levator veli palatini (g), and palatopharyngeus (not shown) muscles are underneath the mucosa of the lateral walls of the nasopharynx. The stylopharyngeus (h) with the palatopharyngeus muscles add to the stability of the roof of the nasopharynx.

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41
Q
A

Figure 45-3. The intrinsic structures of the nasopharynx viewed from the ventral aspect of the nasopharynx, showing the muscles of the soft palate, the palatine aponeurosis (d), and the hamulus of the pterygoid bone (arrow). a, Tensor veli palatini muscle; b, levator veli palatini muscle; c, palatinus muscle.

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42
Q
A

Figure 45-4. The intrinsic muscles that form the wall and roof of the nasopharynx. Note that contractions of the stylopharyngeus caudalis support the roof of the nasopharynx.

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43
Q

What is the primary structural composition of the pharynx?

A

The pharynx is a musculomembranous tubular structure unsupported by bone or cartilage.

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44
Q

What are the three anatomical divisions of the pharynx?

A

The nasopharynx, oropharynx, and laryngopharynx.

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45
Q

How does the soft palate affect communication between the nasopharynx and oropharynx?

A

The soft palate prevents communication by contacting the subepiglottic tissue.

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46
Q

What is the pressure range (in cm H2O) that the nasopharynx must withstand during respiration?

A

The nasopharynx withstands pressures from 24 to 50 cm H2O.

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47
Q

What airflow velocity can the nasopharynx accommodate?

A

The nasopharynx can accommodate airflow velocities up to 90 L/s.

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48
Q

What role do intrinsic muscles play in the nasopharynx?

A

Intrinsic muscles stabilize the nasopharynx by contracting to tense and dilate its walls.

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49
Q

Which muscle is responsible for tensing the rostral aspect of the soft palate?

A

The tensor veli palatini muscle.

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50
Q

Which nerve innervates the tensor veli palatini muscle?

A

The mandibular branch of the trigeminal nerve.

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51
Q

What is the function of the palatinus muscle?

A

The palatinus muscle shortens and depresses the soft palate toward the tongue.

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52
Q

Which nerve innervates the palatinus and palatopharyngeus muscles?

A

The pharyngeal branch of the vagus nerve.

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53
Q

What is the role of the extrinsic musculature in the nasopharynx?

A

Extrinsic muscles increase respiratory patency and stability of the nasopharynx.

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54
Q

What is the primary action of the hyoglossus muscle?

A

The hyoglossus muscle retracts and depresses the base of the tongue.

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55
Q

Which muscle is primarily involved in the dorsal displacement of the soft palate during exercise?

A

Dysfunction of extrinsic muscles leads to dorsal displacement of the soft palate.

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56
Q

What anatomical structure do the genioglossus and geniohyoideus muscles attach to?

A

They attach to the basihyoid bone.

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57
Q

How does the contraction of the thyrohyoideus muscle affect the larynx?

A

It enhances stability by moving the larynx rostrad during exercise.

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58
Q

Which are the extrinsic muscles?

A
  1. geniohyoideus
  2. thyrohyoideus
  3. genioglossus
  4. hyoglossus
  5. hyoepiglotticus
    6.styloglossus
  6. stenohyoideus
  7. sternothyroideus muscles
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58
Q

What anatomical disorder is characterized by a web of scarring in the nasopharynx?

A

Nasopharyngeal cicatrix.

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59
Q

Describe the genioglossus

A

The genioglossus muscle is a fan-shaped extrinsic tongue muscle that originates within the median plane of the tongue and attaches to the oral surface of the mandible, caudal to the symphysis

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60
Q

What happens when genioglossus muscle contracts

A

Contraction of the genioglossus muscle protracts the tongue and pulls the basihyoid bone rostrally.

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60
Q

The styloglossus muscle lies on the lateral aspect of the tongue, originates on the lateral aspect of the stylohyoid bone and inserts on the tip of the tongue. Its function is

A

retraction of the tongue (i.e., retruder)

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61
Q

The hyoglossus muscle is located medial to the styloglossus muscle, originates on the

A

hyoid bones (lingual process, stylohyoid and thyrohyoid bone), and inserts on the median plane of the dorsum of the tongue.

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62
Q

Because local anesthesia of the hypoglossal nerve at the midlevel of the ceratohyoid bone interferes with the action of the___________ and ___________ muscles (protruders of the tongue) at the same time as that of styloglossus and hyoglossus (retruders), the exact function of each paired muscle is not yet known

A

ceratohyoid bone interferes with the action of the geniohyoideus and genioglossus muscles (protruders of the tongue)

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63
Q

The sternothyroideus muscle inserts on the caudolateral aspect of the thyroid

A

thyroid cartilage

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64
Q

the sternohyoideus muscle inserts on the basihyoid bone and ________ (1 w) process of the hyoid apparatus.

A

sternohyoideus muscle inserts on the basihyoid bone and lingual process of the hyoid apparatus.

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65
Q

______________ (1w) muscle, attaches to the hyoid bone at the base of the epiglottis, and during its contraction, pulls the epiglottis ventrad toward the base of the tongue

A

hyoepiglotticus muscle, attaches to the hyoid bone at the base of the epiglottis, and during its contraction, pulls the epiglottis ventrad toward the base of the tongue

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65
Q

Contraction of sternothyroideus, sternohyoideus results in caudal traction on the________ (1w)apparatus and larynx.

A

Contraction of these muscles results in caudal traction on the hyoid apparatus and larynx.

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66
Q

What is the only muscle that inserts on the epiglottis

A

hyoepligotticus muscle

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67
Q

___________________(1w) muscle, which extends from the lateral lamina of the thyroid cartilage to the caudal aspect of the thyrohyoid bone

A

thyrohyoideus muscle, which extends from the lateral lamina of the thyroid cartilage to the caudal aspect of the thyrohyoid bone

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68
Q

disruption of the thyrohyoideus muscle results in….(1w)

A

DDSP

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68
Q

The hypoglossal nerve innervates which muscles

A

geniohyoideus m.(main branch)
genioglossus m. (medial branch)
styloglossus m.
hyoglossus m. (lateral branch)
hyoepiglotticus m. (main granch)

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69
Q

The first and seconde cervical nerves innervate which muscles?

A

Sternohyoideus
Sternothyroideus

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70
Q

Arterial blood supply to the pharynx is provided by the

A
  1. common carotid
  2. external carotid arteries
  3. linguofacial trunk
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71
Q

The extrynsic muscles the drainage is from

A

retropharyngeal and cranial cervical lymph nodes

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72
Q

Which nerves provide sensosry innervation to the nasopharyngeal mucosa?

A

Trigeminal n.
vagus n.
glossopharyngeal n.

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73
Q

Nasopharyngeal cicatrix has a predisposition for

A

mares 60%

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74
Q
A

Figure 45-5. Endoscopic photograph of a nasopharyngeal cicatrix in a horse, characterized by scar formation across the floor of the nasopharynx.

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75
Q
A

Figure 45-6. Endoscopic photograph of a nasopharyngeal cicatrix affecting the larynx and epiglottic cartilage. Note the deformation of right arytenoid cartilage, as well as scar formation across the floor of the nasopharynx

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76
Q

What percentage of nasopharyngeal cicatrix cases show epiglottic or arytenoid cartilage deformation?

A

Nearly 95%.

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76
Q

In which climate is nasopharyngeal cicatrix more commonly reported?

A

Hot climates, especially in the eastern and southern United States.

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77
Q

What is the typical age range of horses affected by nasopharyngeal cicatrix?

A

Affected horses range from 5 to 29 years.

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78
Q

What is a common clinical sign of nasopharyngeal cicatrix?

A

Upper respiratory noise.

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78
Q

What types of primary nasopharyngeal masses are mentioned?

A

Benign lesions, tumors, and ethmoid hematomas.

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79
Q

What is a potential treatment for fungal granulomas in the nasopharynx?

A

Weekly intralesional injections of amphotericin B.

80
Q

What are common clinical signs of nasopharyngeal masses?

A

Exercise intolerance, respiratory noise, and nasal drainage.

81
Q

What surgical approach is used for endoscopy-assisted mass resection?

A

A diode laser is used to incise the base of the mass.

81
Q

What anatomical feature is often evaluated when diagnosing nasopharyngeal masses?

A

Adjacent structures like the nasal cavity and paranasal sinuses.

82
Q

What preoperative medication is given to horses undergoing endoscopy-assisted resection?

A

Dexamethasone and phenylbutazone.

82
Q

Which muscle is unique for its insertion on the epiglottis?

A

Increased upper airway pressure during exercise.

83
Q

What is the role of the hypoglossal nerve in nasopharyngeal function?

A

It innervates several muscles involved in tongue and hyoid movement.

84
Q

How does the contraction of the geniohyoideus muscle affect the hyoid apparatus?

A

It draws the hyoid apparatus rostrally and protrudes the tongue.

85
Q

What is a possible treatment for nasopharyngeal masses if mass resection is not feasible?

A

Intralesional injection of formaldehyde.

86
Q

What is the role of the caudohyoid muscles in nasopharyngeal function?

A

They exert caudal traction on the hyoid apparatus and larynx.

87
Q

What anatomical structure is described as the ‘lateral pillars of the soft palate’?

A

The caudal free margin of the soft palate.

88
Q

How is the nasopharyngeal function impacted by age-related changes?

A

Increased scarring and reduced diameter can lead to functional abnormalities.

89
Q

What s the long-term results of tracheostomy in horses with nasopharingeal cicatrix with associated chondritis?

A

Very good long-term results have been reported after permanent tracheostomy for treatment of this condition in horses

89
Q

What physiological change is associated with DDSP during exercise?

A

Dorsal displacement of the soft palate, leading to airway obstruction.

90
Q

What is the tx for nasopharyngeal cicatrix?

A

The horse should be removed from pasture and anitinflammatory therapy initiated if needed transect obstruction with diode lase

91
Q

What dosage of dexamethasone is administered preoperatively in mass resection?

A

0.044 mg/kg.

92
Q

Which antifungal agent is used for treating fungal granulomas?

A

Amphotericin B.

93
Q

What is the method of access for a pharyngotomy?

A

Through the caudal edge of the soft palate.

94
Q

What are the major disadvantages of the pharyngotomy approach?

A

Limited exposure and potential damage to the hyoepiglotticus muscle or its innervation = epiglottic retroversion during exercise –> only do pharyngotomy if oral or laryngo is not an option

95
Q

What is the premedication for mass removal?

A

Preoperatively, horses are administered dexamethasone (0.044 mg/kg) and phenylbutazone (4.4 mg/kg) intravenously. Postoperatively, the steroids are continued for 2 to 3 days and the nonsteroidal antiinflammatory drug (NSAI D) for 3 to 5 days. In addition, 20 mL of throat flush solution (composed of 250 mL of glycerin, 250 mL of 90% dimethyl sulfoxide [DMSO ], 500 mL of nitrofurazone, and 50 mL of prednisolone 25 mg/mL) is administered twice a day using a 12-French red rubber feeding tube and alternating nostrils between treatments.

96
Q

What is the throath flush solution?

A

250 mL glgycerin
250 mL of 90% DMSO
500 mL nitrofurazone
50 mL prednisolone (25mg/mL) administered twice a day using a 12-French red rubber feeding tube and alternating nostrils between treatments

97
Q

Which instruments do you use to remove a mass in the nasopharynx?

A

Laryngeal forceps or use a snare and with diode lase (12-15 watts) you incise the mass after LA

98
Q
A

Figure 45-8. Endoscopic view of a pharyngeal mass in a 20-year-old horse. The mass originated from the root of the tongue

99
Q

What are the surgical approaches of the oropharynx?

A
  1. orally
    2.0 orally after mandibular symphysiotomy or pharyngotomy
  2. laryngotomy via incision of the cricothyroid ligament
100
Q

Describe pharyngotomy

A

With the horse under general anesthesia and in dorsal recumbency, the ventral aspect of the basihyoid bone and thyroid cartilage is palpated on the ventral midline

101
Q
A

Figure 45-10. Pharyngotomy. The sternohyoideus muscles have been bluntly separated, allowing exposure to the underlying fascia. The basihyoid has been split longitudinally with an osteotome (an optional step), and the superficial fascia is being incised with curved Mayo scissors, exposing the underlying hyoepiglotticus muscle
The skin incision is extended from the rostral aspect of the thyroid cartilage forward toward the basihyoid bone. The sternohyoideus muscles are separated bluntly on the ventral midline, and the incision is extended to the loose fascia between the thyroid cartilage and the basihyoid bone (fig 45-10) The hyoepiglotticus muscle is enclosed in elastic fascia (hyoepiglotticus ligament) deep to the loose fascia. The left and right hyoepiglotticus muscles are separated on the midline, and the incision is extended through multiple layers of loose fascia until the oropharyngeal mucosa is reached. Further exposure is obtained by splitting the basihyoid longitudinally with an osteotome. Malleable or Langenbeck retractors are needed to retract each side of the incision laterad and the root of the tongue rostrad.

101
Q
A

Figure 45-9. Pharyngotomy. Schematic shows the view of the ventral cervical area of a horse in dorsal recumbency and illustrates the landmarks for a pharyngotomy. The bold line represents the line of incision extending from the basihyoid to the thyroid cartilage.

102
Q

How is the oropharyngeal muscosa closed?

A

T
he oropharyngeal mucosa is closed using No. 0 poliglecaprone (Monocryl) in a simple-continuous pattern. A few simple-interrupted sutures are used to reappose the loose areolar tissue ventral to the oropharyngeal mucosa. The basihyoid (if it was split) is reapposed using a simple No. 2 steel suture. The sternohyoideus muscle is sutured using a No. 0 polyglactin 910 or No. 0 poliglecaprone 25 in a simple-continuous pattern. The subcutaneous tissue and skin are closed only over the split basihyoid bone. Complete closure is not recommended because of the clean-contaminated nature of the incision

103
Q

Complete closure is recommended in the pharyngotomy?

A

Complete closure is NOT recommended because of the clean-contaminated nature of the incision

104
Q

What anatomical structure is palpated during a laryngotomy?

A

The basihyoid bone and thyroid cartilage.

105
Q

What muscle is separated during the pharyngotomy procedure?

A

Sternohyoideus muscles.

106
Q

What type of suture is used to close the oropharyngeal mucosa?

A

Sternohyoideus muscles.

107
Q

What type of suture is used to close the oropharyngeal mucosa?

A

No. 0 poliglecaprone (Monocryl).

108
Q

What condition may be indicated by rostral pharyngeal collapse?

A

Fluttering of the rostral aspect of the soft palate.

108
Q

How is rostral pharyngeal collapse experimentally induced?

A

Bilateral transection of the tensor veli palatini tendon.

109
Q

What is the main clinical sign associated with rostral pharyngeal collapse?

A

Upper respiratory noise.

110
Q

What systemic treatment is commonly used for nasopharyngeal inflammation?

A

Dexamethasone.

111
Q

What is the function of a dropped or figure-of-eight nose band?

A

To prevent airflow into the oropharynx.

112
Q

What method is suggested for decreasing palatal compliance?

A

Laser thermoplasty.

113
Q

What are the characteristics of the custom-built “irons” used in thermal palatoplasty?

A

Two 1-cm-diameter steel rods with a T-shaped end.

114
Q

What area of the soft palate is cauterized during thermal palatoplasty?

A

The ventral surface extending caudad beyond the palatoglossal arch.

115
Q

How many days postoperatively is phenylbutazone administered?

A

3 to 5 days.

116
Q

How is access to the oropharynx achieved through laryngotomy?

A

Incision of the cricothyroid ligament.

116
Q

What is the surgical approach for removing a subepiglottic mass?

A

pharyngotomy or laryngotomy.

116
Q

What condition might palatal instability (PI) indicate?

A

It may be a precursor to DDSP.

117
Q

What are the signs of iodine toxicity in treated horses?

A

Dry skin.

117
Q

What is a potential consequence of unsuccessful palatoplasty techniques?

A

Ineffective long-term reduction of soft palate compliance.

118
Q

What is the medical tx of rostral pharyngeal collapse?

A

M
edical treatment consists of reducing any nasopharyngeal inflammation with the use of local and systemic antiinflammatory agents. For an average 450-kg horse, the authors have used either systemic dexamethasone (30 mg IV or PO SI D for 3 days, followed by 20 mg IV or PO SI D for 3 days, then 10 mg IV or PO SI D for 3 days, and finally 10 mg IV or PO every other day for three treatments) or aerosol fluticasone (3 mg BID, or 2200 μg 10 puffs SI D) and topical antiinflammatory solution containing glycerin, DMSO , dexamethasone, and nitrofurazone. The authors also administer 20 mL of a throat flush solution BID (composition described earlier). In addition, one author (Norm G. Ducharme) empirically recommends a dropped or figure-of-eight nose band to prevent airflow into the oropharynx

119
Q

What are the surgical tx of rostral pharyngeal collapse?

A

Thermal Palatoplasty
Tension
Both performed by oral approach

119
Q
A

Figure 45-13. Thermal rostral palatoplasty. (A) Rostral aspect of the soft palate viewed through the oropharynx immediately before surgery. Note parasagittal longitudinal folds on the oropharyngeal mucosa of the rostral aspect of the soft palate. (B) Appearance of the soft palate immediately after cauterizing.

120
Q

Tension Palatoplast the horse is under GA and an elliptical incisio is made where?

A

elliptical incision is made throguh the oral mucosa starting immediately caudal to the caudal edge of the hard palate two thirds of rostal soft palate mucosa and submucosa (9-12 cm by 1-2 cm wide) using long handled forceps and metzenbaum scissors

121
Q

What is the prognosis in case of tension palatoplasty?

A

GUARDED Prognosis is related to the degree of collapse. A guarded prognosis should be given because the current knowledge of this condition is limited

121
Q
A

Figure 45-14. Tension rostral palatoplasty. Schematic drawing shows the location of the elliptical incision (dotted line) on the ventral and rostral aspect of the soft palate as viewed though the oropharynx. This incision leads to resection of the oropharyngeal mucosa and glandular portion of the soft palate in that specific location. a, Hard palate; b, isthmus faucium; c, sagittal fold; d, caudal border of the soft palate.

122
Q

How long is the incision in the tension palatoplasty?

A

elliptical section of approximately two thirds of the rostral soft palate mucosa and submucosa is excised (9 to 12 cm long by 1 to 2 cm wide)

123
Q

The mucosal and submucosal edges are reapposed using what sutures in the tension palatoplasty?

A

No. 0 Vicryl or Monocryl in a simple-interrupted pattern. The procedure can be repeated in 4 weeks (a procedure termed maximum tension palatoplasty) to further increase the tension in the soft palate.

124
Q

The degree of postoperative pain is worse in the thermal or tension?

A

The degree of postoperative pain is reportedly minimal and of short duration after thermal palatoplasty (2–3 days) compared with tension palatoplasty (up to 7 days in some cases).

125
Q

What are the two types of displacement associated with nasopharyngeal collapse?

A

Unilateral or bilateral ventral displacement of the roof and medial displacement of the lateral walls.

126
Q

During what phase of exercise does the roof of the nasopharynx normally collapse?

A

At the end of expiration.

127
Q

What muscle dysfunction is linked to collapse of the nasopharyngeal roof?

A

Dysfunction of the stylopharyngeus caudalis muscle.

128
Q

Which systemic diseases could contribute to nasopharyngeal collapse?

A

Hyperkalemic periodic paralysis (HYPP), botulism, and equine protozoal myelitis.

128
Q

What can cause intraluminal collapse of the lateral walls of the nasopharynx?

A

Dysfunction of the palatopharyngeus muscles.

129
Q

What happens to the nasopharyngeal lumen during clinical disease?

A

It reduces to a diameter less than the cross-sectional diameter of the rima glottidis.

129
Q

At what age are dynamic dorsal pharyngeal collapses most commonly observed?

A

In 2- and 3-year-old racehorses.

129
Q

What has been speculated regarding the capacity to equilibrate the pressures of GPouch and nasopharynx?

A

has been speculated that some horses have failure to equilibrate the pressures between the nasopharynx and the guttural pouches especially with head flexion

130
Q

In the clinical disease, collapse of the nasopharynx occurs during inhalation or exhalation?

A

inhalation, reducing its lumen to a diameter less than the cross-sectional diameter of the rima glottidis

130
Q

What are the clinical signs of dynamic dorsal pharyngeal collapse?

A

Inspiratory upper respiratory noise and exercise intolerance.

131
Q

What diagnostic method can suspect dorsal/lateral nasopharyngeal collapse?

A

Endoscopic examination during nasal occlusion.

132
Q

What is the estimated prevalence of intermittent DDSP in a population of horses?

A

1.3% in a study of 479 horses.

132
Q

What is the likely prevalence of DDSP in 2- to 3-year-old racehorses?

A

Closer to 10% to 20%.

133
Q

Why is the horse considered an obligate nasal breather?

A

To allow olfactory senses to function during deglutition.

133
Q

What anatomical relationship exists between the epiglottis and soft palate?

A

The epiglottis normally positions dorsal to the soft palate.

134
Q

What is a consequence of dorsal displacement of the soft palate?

A

Airway obstruction due to the caudal free margin billowing across the rima glottidis.

135
Q

What percentage of horses with DDSP are considered “silent displacers”?

A

Approximately 20% to 30%.

135
Q

What digestive disturbances may accompany DDSP?

A

Feed, water, and saliva contamination of the upper airways.

135
Q

How does DDSP affect upper airway pressure during exercise?

A

It creates expiratory obstruction, increasing tracheal expiratory pressure and impedance.

136
Q

What three anatomical deficits can cause dysphagia in horses with DDSP?

A

Damage to the palatinus/palatopharyngeus muscles, cleft palate, or mechanical deficits from laryngeal prosthesis.

137
Q

What role does the palatopharyngeal arch play during normal function?

A

It converges dorsad, aiding in maintaining airway patency.

138
Q

What does endoscopic examination during exercise help diagnose?

A

Accurate diagnosis of conditions like DDSP

139
Q

What should clinicians look for in the guttural pouches during examination?

A

The primary cause of nasopharyngeal collapse.

140
Q

What type of protocol should be considered for young horses with nasopharyngeal issues?

A

An anti-inflammatory protocol.

141
Q

What should medical treatment focus on for nasopharyngeal collapse?

A

Resolving the primary condition causing the collapse.

142
Q

What surgical options are available for nasopharyngeal collapse?

A

Procedures like removal of plica salpingopharyngea or nasopharyngeal fenestration that can equilibrate the pressures btw GP and nasopharynx

143
Q

What experimental treatments are being researched for nasopharyngeal collapse?

A

Specific treatments are under investigation, but none are stabilizing yet.

144
Q
A

Figure 45-17. Fenestration of the nasopharynx facilitating rapid equilibration of the airway pressures between the nasopharynx and the guttural pouches. In this horse laser fenestration was made at the nasopharyngeal recess.

145
Q

When the soft palate displaces dorsad what canoot be seen?

A

The epiglottis cannot be seen in the nasopharynx

146
Q

DDSP with dysphagia generally indicates 3 situtations, name them

A

1) a more-advanced deficit of the palatinus/palatopharyngeus muscles (or their innervation); (2) an anatomic deficit, such as cleft palate or an acquired deficit of the caudal free edge of the soft palate after staphylectomy or loss of epiglottic cartilage secondary to septic epiglottis or surgical trauma; or (3) a mechanical deficit after placement of laryngeal prosthesis that allows feed contamination of the nasopharynx from the oropharynx.

147
Q

DDSP with dysphagia should be differentiate from what?

A

from aspiration of feed material into the trachea from laryngeal disease (or its treatment), which can lead to DDSP , presumably by inducing ventral and caudal laryngeal movement/displacement.

148
Q

How does DDSP impact ventilation in affected horses?

A

It primarily interferes with ventilation during intense exercise.

149
Q

What factors may worsen DDSP during exercise?

A

Increased upper airway resistance or mechanical issues related to the soft palate.

150
Q

WhatWhat anatomical feature is critical in creating a tight seal during deglutition?

A

The contact between the epiglottis and the soft palate.

151
Q

What is one of the key measurements in diagnosing DDSP during exercise?

A

Upper airway mechanics.

152
Q

How is the treatment approach for DDSP influenced by the underlying cause?

A

Treatment varies significantly based on whether the cause is structural, muscular, or functional.

153
Q
A

Figure 45-19. (A) Palatal granuloma in a 2-year-old Thoroughbred with dorsal displacement of the soft palate. (B) Appearance of the granuloma dorsal to the palate and ventral to the epiglottic cartilage (arrows) with the soft palate replaced

154
Q
A

Figure 45-21. Bruising of nasopharynx approximately 12 hours following racing in a 7-year-old Standardbred gelding. This supports a diagnosis of dorsal displacement of the soft palate during racing.

155
Q
A

Figure 45-20. Ulcer on the free edge of the soft palate in a 3-year-old Standardbred. This finding supports a diagnosis of DDSP and can also be seen if a subepilgottic mass or lesion is present.

156
Q

What early hypotheses were proposed for DDSP?

A

Paralysis of the palate muscles and elongation of the soft palate.

157
Q

What mechanical factors are associated with DDSP according to anecdotal evidence?

A

Cysts and other lesions on the soft palate that interfere with its position.

158
Q

What effect do cysts on the soft palate have on DDSP?

A

They mechanically interfere with the normal subepiglottic position, and their removal can correct DDSP.

159
Q

What are examples of lesions that may cause DDSP?

A

Subepiglottic or palatal granulomas, masses, and cysts.

160
Q

How is epiglottic hypoplasia related to DDSP?

A

It may prevent the epiglottis from maintaining the soft palate in a subepiglottic position.

161
Q

What clinical sign is associated with horses that have a flaccid epiglottis?

A

A decrease in racing performance, particularly in yearlings.

162
Q

What is palatal instability?

A

Billowing of the soft palate that often precedes DDSP.

163
Q

How does the position of the basihyoid bone relate to DDSP?

A

A more ventral position of the basihyoid bone is associated with DDSP.

164
Q

What has been observed about horses with permanent DDSP?

A

They have a more caudal position of the larynx compared to those with intermittent DDSP.

165
Q

What experimental model demonstrated the role of the vagus nerve in DDSP?

A

The blockade of the pharyngeal branch of the vagus nerve model.

166
Q

What muscle is primarily responsible for stabilizing the soft palate at rest?

A

The palatinus muscle.

167
Q

What are the common clinical signs of intermittent DDSP in racehorses?

A

Exercise intolerance and gurgling or vibrating noises during exhalation.

168
Q

What is the predictive value of resting endoscopic examination for DDSP?

A

It has a poor predictive value, leading to misdiagnosis 35% of the time.

169
Q

What is the gold standard for diagnosing intermittent DDSP?

A

History of poor performance, respiratory noise, and endoscopic examination during exercise.

170
Q

Why is treadmill examination more effective for diagnosing DDSP in racehorses?

A

Because it allows for maximal exercise intensity, which is crucial for identifying DDSP.

171
Q

What surrogate evidence can indicate DDSP in a resting exam?

A

Ulceration on the caudal edge of the soft palate or bruising on the nasopharynx.

172
Q

What are some treatments for upper respiratory tract inflammation associated with DDSP?

A

Systemic anti-inflammatory medications and topical anti-inflammatory solutions.

173
Q

What is the success rate reported for nonsurgical treatments for DDSP?

A

A 53% to 61% success rate.

174
Q

What devices are used to prevent DDSP during exercise?

A

Throat-support devices and figure-of-eight nosebands.

175
Q

What anatomical changes are hypothesized to lead to DDSP?

A

Increased compliance of the soft palate due to inappropriate muscle contraction.

176
Q

What is the effect of a tongue-tie on DDSP?

A

It may help prevent caudal retraction of the tongue, potentially stabilizing the soft palate.

177
Q

What role does the thyrohyoideus muscle play in DDSP?

A

It helps decrease the collapsibility of the nasopharynx during exercise.

178
Q

What are the implications of the laryngeal tie-forward surgery findings?

A

Dorsal positioning of the basihyoid bone improves postoperative outcomes.

179
Q

What happens to the larynx during episodes of DDSP?

A

Caudal retraction of the larynx can occur, leading to displacement.

180
Q

How can mouth opening during exercise affect DDSP?

A

It allows air into the oropharynx, disturbing subatmospheric pressure that stabilizes the soft palate.

181
Q

What is the effect of caudal retraction of the tongue on the soft palate?

A

It may push the soft palate dorsad, inducing DDSP.

182
Q

What anatomical position is believed to confer stability to the soft palate?

A

A dorsal position of the larynx and basihyoid bone.

183
Q

What other respiratory conditions are commonly associated with DDSP?

A

Upper respiratory inflammatory diseases such as pharyngitis.

184
Q

In case of DDSP if there are no structural abnormalities (cyst, granulomas, epiglottic entrapment) shoud we go for surgery?

A

NO, nonsurgical management should be used first

185
Q

nasopharyngeal and guttural pouch inflammation can lead to dysfunction of the pharyngeal branch of the _______(1w) nerve

A

nasopharyngeal and guttural pouch inflammation can lead to dysfunction of the pharyngeal branch of the vagus nerve

186
Q

If the vagus nerve (due to GP and ansopharygenal inflammation) is affected what other 2 muscles are affected leading to DDSP?

A

palatinus and palatopharyngeus muscle tone, leading to PI and/or DDSP .

187
Q

What should include the medical tx of DDSP?

A

If upper respiratory tract inflammation is diagnosed, treatment should include judicious use of systemic antiinflammatory medication (dexamethasone as described earlier or aerosol fluticasone 3 mg BID, or 220 mcg/puff, 20 puffs every 24 hours) and topical antiinflammatory solution containing glycerin, DMSO , dexamethasone, and nitrofurazone.
horse’s head position, and a figure-of-eight noseband

188
Q

Give % success rate when nonsurgical treatments were used alone for DDSP

A

53% to 61% for DDSP

189
Q

previously for treatment of rostral palate instability, have been shown recently to be ineffective for treatment of DDSP TRUE or FALSE?

A

True