Anatomy_Key Terms_Ch18 Flashcards
blood
transport medium for carrying nutrients, signaling molecules, respiratory gases, and waste products to and from our body tissues
hematocrit
”"”blood fraction””, percentage of the blood volume that consists of erythrocytes<br></br>47+-5% in healthy men, 42+-5% in healthy women, averages 45%”
buffy coat
thin, gray layer present at the junction between the erythrocytes and the plasa, contains leukocytes and platelets
blood plasma
straw-colored, sticky fluid, 90% water, contains over 100 different kinds of molecules, plus three main proteins (albumin, globulins, fibrinogen)
albumin
helps keep water from diffusing out of the bloodstream into the extracellular matrix of tissues
globulins
include both antibodies and the blood proteins that transport lipids, iron, and copper
fibrinogen
plasma protein, one of several molecules involved in a series of chemical reactions that achieves blood clotting
formed elements of blood
aka blood cells, neither erythrocytes nor platelets are true cells (erythrocytes lack nuclei and organellse and platelets are merely cell fragements); most of the formed elements cannot divide, they survive in the bloodstream for only a short time (hours to months) before being replaced by new cells produced in the bone marrow
erythrocytes
aka red blood cells (RBCs), small, oxygen-transporting cells ~7.5um, by far the most numerous formed element, ~25t in a healthy adult
leukocytes
“aka white blood cells (WBCs), crucial to the body’s defense against disease, roughly spherical in shape, complete cells, 4800-11000/cubic mm”
diapedesis
”"”leaping through””, process wherein leukocytes leave the cappillaries by actively squeezing between the endothelial cells that form the capillary walls”
leukocytosis
a leukocyte count exceeding 11000 per cubic mm indicates infection or inflammation; the patient is said to have _
granulocytes
neutrophils, eosinophils, basophils, contain many obvious granules
agranulocytes
lymphocytes, monocytes, lack obvious granules
neutrophils
most abundant class of leukocyte, destroy bacteria, nucleus consists of 2-6 lobes interconnected by very thin therads of chromatin
pus
forms in areas of bacteral infection, is composed of dead neutrophils and other leukocytes, plus tissue debris and dead bacteria
eosinophils
usually has two lobes interconnected by a broad band, play a role in ending allergic reactions by phagocytizing allergens after the allergens are bound to antibodies
lymphocytes
each recognizes and acts against a specific foreign molecule; two main classes of T cells and B cells
antigen
”"”induce against””, molecule that induces a response from a lymphocyte”
T cells
bind to antigens that are presented by special proteins that occur only on the membranes of eukaryotic cells
B cells
differentiate into plasma cells that secrete antibodies
antibodies
proteins that bind to the antigen and thus mark the foreign cell for destruction by macrophages
monocytes
nucleus often bent into kidney or horseshoe, and nuclear chromatin is not as condensed (dark) as that in symphocites, use tho bloodstream to reach the connective tissues, transform into macrophages
macrophages
phagocytic cells that move by amoeboid motion through connective tissue and ingest a wide variety of foreign cells, molecules, and tiny particles of debris
platelets
aka thrombocytes (clotting cells), disc-shaped plasma membrane-enclosed fragments of cytoplasm that form by breaking off of larger cells called megakaryocytes; plug small tears in the walls of blood vessels to limit bleeding
clotting
a sequence of chemical reactions in blood plasma that ultimately generates a network of tough fibrin strands among the accumulated platelets
clot
mass consisting of fibrin strands, platelets, and any blood cells that are trapped by the strands
hematopoiesis or hemopoiesis
(hemo, hemato=blood, poeisis=to make), the process by which blood cells are formed
bone marrow
occupies the interior of all bones; two types of bone marrow, red and yellow
yellow marrow
dormant, makes blood cells only in emergencies that demand increased hematopoiesis
red marrow
actively generates blood cells; red hue derives from the immature erythrocytes int contains
hemopoietic stem cell
all blood cells arise from one cell type; in response to growth signals from the nearby reticular cells, they dividue continuously, both to renew themselves and to produce lines of progenitor cells that lead to the various blood cells
lymphoid stem cells
give rise to lymphocytes
myeloid stem cells
give rise to all blood cells except lymphocytes
proerythroblasts
”"”earliest red-formers””, committed cells in the line that forms erythrocytes, avidly accumalate iron for future production of hemoglobin”
basophilic erythroblasts
ribosome-producing factories, on which hemoglobin is made and accumulates during the next two stages: polychromatic erythroblast and orthochromatic erythroblast
reticulocyte
a young erythrocyte that contains a network of blue-staining material representing clumps of ribosomes that remain after the other organelles are extruded, enter the bloodstream and begin the task of trasporting oxygen
myeloblasts
committed cells in each granulocyte line
promyelocytes
myeloblasts that have accumlated lysosomes
mylocyte
stage three when the distinctive granules of each granulocyte appear, cell division ceases