Alzheimer Flashcards
1
Q
dědičnost
A
Autosomal dominant: 3+ individuals in 2+ generations affected. 2 individuals must be 1st degree relatives of the third. Offer genetic testing.
Familial: More than one individual is affected and 2+ affected individuals are at least 3rd degree relatives.
**-Sporadic: **Isolated or when individuals are separated by more than 3 degrees.
2
Q
Early Onset Alzheimers Disease (EOAD)
A
Onset of symptoms prior to 65 years
Offer genetic testing for APP, PSEN1, PSEN2 with adequate counseling, a full neuro-phsycological and neurological evaluation
