3rd Semester Pharm Final Flashcards

1
Q

Zofran (odansetron)

A

Antiemetic usedto prevent nausea and vomiting after surgery, gastroenteritis, cancer chemo, or radiation therapy

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2
Q

Neupogen

A

Drug for shortening WBC recovery period after chemotherapy, preventing pancytopenia

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3
Q

Cyclophosphamide

A

Alkylating chemotherapy drug used to suppress immune system treating lymphoma, leukemia, etc.

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4
Q

Methotrexate

A

Chemotherapeutic agent and immunosuppressant to treat cancers as well as RA and psoriasis

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5
Q

Cyclosporine

A

Immunosuppressant drug used to prevent organ rejection in patients who have received liver, kidney, or heart transplant

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6
Q

5 FU

A

Antimetabolite chemotherapeutic agent

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7
Q

7+3 therapy

A

Cytabrine and daunorubicin used together for treating AML but should be avoided in cardiac disease

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8
Q

Bisphosphonates

A

Class of drugs that prevent the loss of bone density used to treat osteoporosis and similar diseases

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9
Q

Gleevac (imatinib)

A

Tyrosine kinase used alongside bone marrow transplant for treatment of CML, most common issue is fluid retention

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10
Q

Rituximab (rituxan)

A

Part of R-CHOP formula used to treat certain kidns of cancer such as non hodgekin’s lymphoma and CLL, also immunosuppressant used to treat RA and decrease joint pain and swelling

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11
Q

Cimetidine (tagamet)

A

H2 receptor antagonists that decreases acid secretion and inhibits gastrin for heart burn, stomach ulcers, GERD, ADR’s include antiandrogenic effects

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12
Q

Ranitidine (zantac)

A

H2 receptor antagonist that decreases acid secretion for heart burn, stomach ulcers, GERD, few ADR’s

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13
Q

Omeprazole (prilosec)

A

Proton pump inhibitor that irreversibly binds proton pumps reducing secretion of H+, rebound hypersecretion and headache

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14
Q

Misoprostol

A

Synthetic analogue of prostaglandin used for prevention of gastric ulcers caused by long term NSAID therapy, contraindicated in pregnancy

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15
Q

Calcium carbonate (tums)

A

Simple antacid, adverse effects can result in metabolic alkalosis

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16
Q

Bismuth subsalicylate (pepto-bismol)

A

Treats stomach conditions including diarrhea, gas, heartburn, nausea, and stomach discomfort, belongs to antidiarrheal, adverse effects include black color stool and tinnitus

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17
Q

Methylcellulose

A

Bulk forming agent laxative similar to fiber

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18
Q

Docusate

A

Surfactant to allow water to move into feces for non opioid induced constipation

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19
Q

Polyethylene glycol (miralax)

A

Osmotic laxative

20
Q

Diphenoxylate and atropine(Lomotil)

A

Man made narcotic for acute diarrhea that abuse potential is lowered by atropine

21
Q

Scopolamine (hyoscine)

A

Anticholinergic drug that depresses neuronal activity in the inner ear for motion sickness

22
Q

Loperamide (immodium)

A

Antidiarrheal opioid OTC used to treat diarrhea by suppressinb bowel motility including IBS but does not cross BBB preventing abuse

23
Q

N acetylcysteine

A

Acetaminophen toxicity antidote

24
Q

Physostigmine

A

Anticholinergic toxicity antidote

25
Q

Flumazenil

A

Benzodiazepine toxicity antidote

26
Q

Cholinesterase inhibitors and organophosphate toxicity antidote

A

Atropine

27
Q

Hydroxocobalamin (deriv of B12)

A

Cyanide toxicity antidote

28
Q

Metoclopramide (reglan)

A

can treat gastroparesis in patients with diabetes or GERD as it is a gut motility stimulator and antiemetic, side effect tardive diskinesias permanent if unchecked

29
Q

Terbutaline

A

Drug to inhibit labor

30
Q

Bromocriptine

A

Prevents lactation from occurring

31
Q

Clonidine

A

an alpha agonist antihypertensive and sedative for some tics and such in children

32
Q

Lyrica (pregabalin)

A

GABA analogue used to treat nerve pain including fibromyalgias and treatment of seizures, risk of abuse in opioid abuse disorder patients

33
Q

Gabapentin (neurontin)

A

GABA analogue anticonvulsant and nerve pain medication, can treat seizures and pain caused by shingles, risk of abuse in opioid use disorder patients

34
Q

examples of strong opioid agonists (4)

A
  • fentanyl
  • hydromorphone
  • methadone
  • morphine
35
Q

Examples of moderate to strong opioid agonists (3)

A
  • codeine
  • hydrocodone
  • oxycodone
36
Q

Dextromethorphan/hydrocodone/codeine

A

Opioid with minimal analgesic activity but good antitussive activity to be used in anticough meds

37
Q

Bupenorphine (suboxone (+naloxone) or buprenex)

A

Partial opioid agonist that can be used to prevent withdrawal in opioid use disorder, typically induced and maintained for indeterminate amount of time on medication

38
Q

Naloxone (narcan)

A

used to reverse respiratory and CNS depression caused by opioid agonists

39
Q

Fentanyl

A

Opioid painkiller with potency approx 100x that of morphine

40
Q

Meperedine (demerol)

A

Short term opioid, used for treatment of severe acute pain, short half life and highly irritating but sometimes used for drug induced rigors and shivering analgesia post anesthesic patient

41
Q

Methadone

A

Opioid PO treatment for chronic nociceptive pain, drug abuse treatment programs for opioid addiction, highly addictive and increases risk of overdose risk if combined with other drugs like heroin, does not provide euphoria but does sedate

42
Q

Oxycodone (percocet)

A

Semi synthetic derivative of morphine 9.5 more potent than codeine and 1.5x more potent than PO morphine

43
Q

hydrocodone

A

analgesic activity equivalent to codeine, PO only to relieve pain and suppress cough Most widely prescribed drug in the US,

44
Q

Naltrexone (vivitrol

A

Pure opioid antagonist used for alcohol and opioid abuse by preventing euphoria (but can precipitate withdrawal and has no effect on craving)

45
Q

Tramadol (ultram)

A

Non opioid central acting agent, PO agent for treatment of moderate to severe pain