Weeks 3-8 Development Flashcards
when primary germ layers give rise to tissues and organs; at the end of this period, main organ systems established
organogenesis
organogenesis is an ___ period that occurs from ____
embryonic; week 3-8
neurulation is the process by which the ____ forms the ____
neural plate; neural tube
neurulation occurs in the ____ via _____
ectoderm; notochordal induction
neurulation completed by the end of ____
4th week
four main events of neurulation
- formation of neural plate
- shaping of neural plate
- invagination of neural plate
- closure of neural groove
during neurulation, notochord induces thickening in overlying ____ along midline of ____ forming _____ (these cells make up neuroectoderm)
ectoderm; embryo; neural plate
laterally elevated edges
neural folds
depressed midregion of neural plate
neural groove
neural folds begin to move together and eventually fuse. this fusion begins in ____ and progresses both ___ and ____; this results in the formation of the _____
cervical region (5th somite); cranially; caudally; neural tube
____ fuse at midline (progressing cranially and caudally), forming the ____, which separates from the _____
neural folds; neural tube; ectoderm
neural groove will become the _____
neural canal
until fusion is completed the cranial and caudal ____ allow the ____ to communicate with the _____
neuropores; neural tube; amniotic cavity
closure of these neuropores indicates _____
the end of neurulation
As neural folds fuse, cells at lateral border (crest) of neuroectoderm dissociate, called _____
neural crest cells
neural crest cells undergo _____ transition and enter the underlying _____
epithelial to mesenchymal; mesoderm
mesoderm near midline proliferate to form thickened _____
paraxial mesoderm
more laterally, the mesoderm stays thin, known as _____
lateral plate mesoderm
in between paraxial and lateral plate mesoderm is the ______
intermediate mesoderm
intracellular cavities split lateral plate mesoderm into:
- somatic or parietal layer (lines the amnion)
- splanchnic or visceral layer (lines yolk sac)
the cavity between the somatic/parietal layer and splanchnic/visceral layer is the _____; it is continuous with the _____ on each side of the embryo
intraembryonic cavity; extraembryonic cavity
____ is the organization of the paraxial mesoderm which occurs at the beginning of week 3
somite
at the beginning of week 3, the paraxial mesoderm starts to organize into segments which form ____ to ____ beginning in ____ region; organized pairs called ____
cranially; caudally; occipital; somites
the paraxial mesoderm will give rise to most of the _____, _____and ____
axial skeleton; skeletal muscles; dermis of the back
somites (in pairs)
- 4 occipital (will disappear)
- 8 cervical
- 12 thoracic
- 5 sacral
- 5 lumbar
- 8-10 coccygeal (last 5-7 disappear)