Digestive System Embryology Flashcards
establishes the 3 germ layers of the embryo during 3rd week of development; begins with formation of the primitive streak on the surface of the epiblast
gastrulation
all 3 germ layers contribute to the formation of the ____
GI tract
_____ of the neuroectoderm become neurons of the ______
neural crest cells; enteric nervous system
the mesoderm germ layer contributes to the formation of ____, _____, and _____
connective tissue; muscular components; peritoneal components
the endoderm contributes to ____ of GI tract and ____ of glands
epithelium; parenchyma
____ covers the ventral surface of the embryo and forms the roof of the yolk sac
endoderm
as a result of body folding during the 4th week, the endoderm is incorporated into the embryo to form the _____
primitive gut tube
the specific cells of a gland or organ held together by connective tissue called the stroma
parenchyma
the endoderm gives rise to specific cells (parenchyma) of glands, such as ____ and the ____ and ____ cells of the ______
hepatocytes; exocrine; endocrine; pancreas
the stroma of the glands of the GI tract is derived from _____
visceral mesoderm
during cephalocaudal or cranial caudal folding in the ____ direction progresses, the opening of the gut tube into the yolk sac narrows until it forms a small connection called the ____
sagittal; vitelline (yolk sac) duct
the vitelline duct is between the ____ and the ____
midgut; yolk sac
the vitelline (yolk sac) duct is incorporated into the ____, becomes very narrow, and degenerates with the yolk sac around 2nd-3rd months of development
umbilical cord
the foregut extends from the ____ to _____
oropharyngeal membrane; liver outgrowth
the oropharyngeal membrane separates the ____ from the ____
stomodeum (primitive oral cavity, derived from ectoderm); pharynx (a part of the foregut, derived from endoderm)
in the 4th week, the oropharyngeal membrane ruptures, establishing open connection between ____ and ____
oral cavity; primitive gut
the midgut begins _____ and extends to _____
caudal to liver bud; proximal 2/3 of transverse colon
hindgut is from _____ to _____
distal 1/3 of transverse colon; cloacal membrane
the cloacal membrane separates the ____ (derived from endoderm) from the ____, which is formed by an invaginating pit lined by ectoderm
upper part of the anal canal (derived from endoderm);
lower part of anal canal (from ectoderm)
cloacal membrane breaks down in 7th week to create the opening for the ____
anus
double layer of peritoneum that encloses an organ and connects it to the body wall
mesentery
thin serous membrane that lines walls of abdominal cavity
peritoneum
organs which are completely enclosed in mesentery and connected to wall via mesentery
intraperitoneal
organ that lies against posterior body wall and is covered with peritoneum on anterior surface only
retroperitoneal
the dorsal mesentery is formed via ____ meeting and fusing in the midline
visceral mesoderm layers
the _____, ____, and the _____ are suspended from the posterior body wall via dorsal mesentery
caudal part of the foregut; midgut; major part of the hindgut
the dorsal mesentery extends from the _____ to the _____
lower end of the esophagus; cloacal region of the hindgut
divisions of dorsal mesentery
- dorsal mesogastrium (greater omentum): dorsal mesentery in region of the stomach
- mesoduodenum: dorsal mesentery in region of duodenum
- dorsal mesocolon: dorsal mesentery in region of the colon
- mesentery proper: dorsal mesentery of jejunal and ileal loops
ventral mesentery is derived from the ____
septum transversum
septum transversum is mesodermal tissue that gives rise to the ____ and _____
central tendon of diaphragm; connective tissue in the liver
ventral mesentery exists only in region of ____, ____, and _____
terminal esophagus; stomach; upper part of duodenum
liver grows in the ____ of the septum transversum, dividing ventral mesentery into:
mesenchyme; lesser omentum and falciform ligament
lesser omentum extends from _____, ____ and _____ to the _____
lower portion of esophagus; stomach; upper portion of the duodenum; liver
the falciform ligament extends from ___ to ____
liver; ventral body wall
free inferior margin of the falciform ligament; contains obliterated umbilical vein
round ligament of the liver (ligamentum teres hepatis)
free margin of lesser omentum connecting duodenum and liver; contains portal triad
hepatoduodenal ligament
portal triad components
bile duct, portal vein, and hepatic artery
opening that connects omental bursa (lesser sac) with the rest of the peritoneal cavity (greater sac)
epiploic foramen of winslow
each gut region is supplied by one of the 3 major arteries off the _____
abdominal aorta
foregut is supplied by ____, midgut is supplied by ____, and hindgut is supplied by ____
celiac (trunk) artery; superior mesenteric artery; inferior mesenteric artery
foregut derivatives:
- esophagus
- trachea and lung buds
- stomach
- duodenum (proximal to entrance of bile duct)
- liver
- biliary apparatus (hepatic ducts, gallbladder, bile duct)
- pancreas
appears at ventral wall of foregut at about the 4th week; is initially in open communication with foregut
respiratory diverticulum (lung bud)
foregut divides into _____ (ventral) and _____ (dorsal)
respiratory primordium; esophagus
upper 2/3 of esophagus contains:
striated muscle and vagus nerve
lower 1/3 of esophagus contains:
smooth muscle and splanchnic plexus
when the respiratory diverticulum expands caudally, two longitudinal ridges called ______ separate it from the foregut
tracheoesophageal ridges
the tracheoesophageal ridges fuse to form the _____, thereby dividing the foregut into a dorsal portion (_____) and a ventral portion (_____)
tracheoesophageal septum; esophagus; trachea and lung buds
the stomach appears as ____ of _____ (4th week)
fusiform dilation; foregut
stomach rotates along ____ and _____ axis
longitudinal; anteroposterior
stomach rotates _____ around its longitudinal axis
90 degrees clockwise
the original left side will now face _____
anteriorly
the left vagus nerve will innervate the ____ of the stomach
anterior wall
the original right side will now face _____
posteriorly
the right vagus nerve will innervate the _____
posterior wall of the stomach
concurrent with stomach rotation, the original posterior wall grows faster than the original anterior portion, leading to ____ and ____
greater and lesser curvatures