Histo of the Urinary System Flashcards
the kidneys filter ____, ___, ____, and ____ from the blood to keep it pure
toxins; metabolic wastes; excess water; excess ions
kidneys dispose of ____ wastes from the blood such as:
nitrogenous wastes such as urea, uric acid, and creatinine
the kidneys regulate the balance of ___ and ___/ ___ and ____
waster; electrolytes; acids; bases
the base of the renal pyramids faces the ___ and the apex is the ____
cortex; renal papilla
____ are between renal pyramids
renal columns
the renal cortex contains renal ____ and associated tubules
corpuscles
the renal medulla has ____, ____, and ____
straight tubules; collecting ducts; vasa recta
a renal lobe consists of a renal ____, its overlying ____, and one half of each adjacent renal ____
pyramid; renal cortex; columns
the glomerular capillary bed is unusual in having arterioles going both to it (____) and away from it (_____) instead of a vein going away from it as most; also unusual in having two capillary beds in series (one following the other)
afferent; efferent
path of the vasculature of the kidneys
aorta, renal a, segmental a, interlobar a, arcuate a, interlobar a, afferent arteriole, glomerulus (capillaries), efferent arteriole, peritubular capillaries and vasa recta, interlobar v, arcuate v, interlobar v, renal v, IVC
in filtration, fluid is squeezed out of the ____
glomerular capillary bed
in reabsorption, most nutrients, water, and essential ions are returned to the blood of the ____
peritubular capillaries
secretion moves additional undesirable molecules into ___ from blood of ____
tubule; peritubular capillaries
two parts of the nephron
renal corpuscle and renal tubule
____ is where tubular reabsorption and secretion occurs
renal tubule
each nephron will drain into a _____
collecting tubule
nephron plus its collecting tubule form the _____
uriniferous tubule
type of nephron in which the renal corpuscle is located near the medulla, but still in the cortex
juxtamedullary nephron
____ have their loop of Henle in the renal medulla near its junction with the renal cortex, while ____ have their loop of Henle deep in the medulla
cortical nephrons; juxtamedullary nephrons
the renal corpuscle is where ____ occurs
glomerular filtration
two components to the renal corpuscle
- glomerulus
- Bowman’s capsule (glomerular capsule)
tuft of capillaries composed of 10 to 20 capillary loops.
glomerulus
the glomerular capillaries are supplied by an ____ and drained by an ____
afferent arteriole; efferent arteriole
double-walled epithelial cup that surrounds the glomerulus
bowman’s capsule
there is an internal or ___ layer of bowman’s capsule and an external or ____ layer
visceral; parietal
where afferent / efferent arterioles enter/exit the renal corpusle
vascular pole
where filtrate exits bowman’s space and enters the proximal convoluted tubule
urinary or tubular pole
podocytes are also called _____
visceral epithelial cells
cells in the Bowman’s capsule in the kidneys that wrap around capillaries of the glomerulus
podocytes
podocytes have long processes called ___ or ____ for which the cells are named
foot processes; pedicels
intercellular clefts between the interdigitating pedicels of podocytes that are about 40 nm wide
filtration slits
semipermeable membrane covering filtration slits
slit diaphragm
the renal tubule consists of _____, ____, and _____
- proximal convoluted tubule (PCT)
- Loop of Henle (nephron loop) with descending and ascending limb
- distal convoluted tubule (DCT)
renal tubule is where ____ and ____ occurs
tubular reabsorption; tubular secretion
PCT is confined to the ____ and has ____
renal cortex; simple cuboidal epithelium
PCT has long microvilli called ____ and ___ appearance in slides/pictures
brush border; fuzzy
thick descending limb of the loop of Henle (aka proximal straight tubule) has ____
simple cuboidal epithelial cells
thin descending limb of the loop of Henle has ____
simple squamous epithelial cells
thin ascending limb of the loop of Henle has ____
simple squamous epithelial cells
thick ascending limb of the loop of Henle (aka distal straight tubule) has _____
simple cuboidal epithelial cells
Distal convoluted tubule (DCT) is confined to ____ and has _____, but cells are ___ than in the PCT
renal cortex; simple cuboidal epithelium; smaller
DCT has lots of ____ which makes cells very _____
mitochondria; eosinophilic
____ are fewer are not long in the DCT which means there is no ____
microvilli; brush border
the lumen of the DCT is ____ than the PCT
smoother
structure where afferent arteriole makes contact with ascending limb of loop of Henle
juxtaglomerular apparatus
thickened part of DCT
macula densa
modified muscle cells in arteriole
juxtaglomerular cells
____ + ____ = juxtaglomerular apparatus (JGA)
macula densa; juxtaglomerular cells
collecting ducts collect ____ from ____
urine; DCT
collecting ducts have ____ that appears less specialized than PCT or DCT
simple cuboidal epithelium
____ in the collecting ducts is relatively clear and cell border are usually ____
cytoplasm; distinct
collecting ducts merge and become ____ as they descend through the medulla
larger
___, ___, ____, and ____ all have the same histological structure, with walls becoming thicker closer to the ____
renal calyces; renal pelvis; ureters; urinary bladder; bladder
mucosa of the urinary system composed of ____ and ____
transitional epithelium (urothelium); lamina propria
the muscularis externa of the urinary system is composed of ____ muscle with inner ____, outer ____ layer and outermost ____ layer (distal end of ureter and present in the bladder)
smooth; longitudinal; circular; longitudinal
outermost layer of these urinary structures is ____
adventitia
ureter is a muscular tube about 10-12 inches in length; ureters have a ___ lumen and 2-3 layers of ____
star shaped; smooth muscle
through peristalsis, the ureters propel urine from the ___ to the ____
kidneys; bladder
hollow, distensible, muscular organ; stores urine with average capacity of ____
bladder; 250 mL
in males, the prostatic urethra is ____
urothelium
the membranous urethra is ____ and ____
stratified columnar epithelium; pseudostratified columnar epithelium
the spongy urethra is ____ and ____ and distally _____
stratified columnar epithelium; pseudostratified columnar epithelium; stratified squamous epithelium
the urethra in females is initially ____ and then _____ (occasionally _____)
urothelium; stratified squamous epithelium; pseudostratified columnar epithelium