Vaginitis and Cervicitis

Question 1

Fluconazole

Answer 1

Vaginitis and Cervicitis
Antifungal
- use for Vulvovaginitis caused by Candida Albicans 
- "-conazole"
MOA
- inhibit ergosterol synthesis, resulting in increased cellular permeability and death of the micro-organism
C/I
- pregnant women should only use topical
- oral is c/i

Question 2

Metronidazole, Tinidazole

Answer 2

Vaginitis and Cervicitis
- used For Trichomoniasis
- Drug of Choice for anaerobic gram (-) bacterial infections! (Such as B. Fragilis and B. Thetaiotaomicron)
MOA
- Metronidazole is activated (reduced) by microbial proteins found in anaerobic bacteria and certain protozoa.
- It exerts its bactericidal effects as it releases free radicals. These interact with nucleic acids causing breakage and destabilization

Question 3

Cephalosporin, Azithromycin, (doxycycline)

Answer 3

Vaginitis and Cervicitis

• used For Cervicitis
• used to tx Gonorrhea and Chlamydia

Question 4

Podophyllin resin

Trichloroacetic Acid

Answer 4

Vaginitis and Cervicitis

- used For Genital Warts