Influenza

Question 0

Amantadine

Rimantadine

Answer 0

Influenza
-antiviral used for influenza A only
MOA
-M2 ion channel blocker
-prevents viral uncoating-virus rendered inert

Question 1

Oseltamivir (Tamiflu)
Zanamivir (Relenza)
Peramivir (Rapivab)

Answer 1

Influenza
-anti-viral drug, used for influenza A and B
MOA
-neuraminidase inhibitors
-stops virus release from host cell and even if it does not release, enables virion clumpling
ADE
-nausea
-vomitting
-skin rxns
-neuropsychiatric events
-usually in *Japanese adolescents and adults