Palliative Care

Question 1

Senna

Answer 1

Palliative Care
- *preferred stimulant laxative used to prevent/treat constipation from opioid analgesics
MOA
- stimulate peristalsis to manage opioid induced constipation

Question 2

Lactulose

Answer 2

Palliative Care
- *used for more severe constipation.
MOA
- stimulate peristalsis to manage opioid induced constipation

Question 3

Methylnaltrexone

Answer 3

Palliative Care
- *Rescue Drug for Severe Opioid Induced Constipation
MOA
- stimulate peristalsis to manage opioid induced constipation
- blocks Peripheral opioid receptors, but not central receptors = Preserves Analgesia

Question 4

Megestrol

Answer 4

Palliative Care
- for Cachexia (Wasting) and Loss of Appetite
MOA
- Progestrones ↑Appetite

Question 5

Dexamethasone

Answer 5

Palliative Care
- for Cachexia (Wasting) and Loss of Appetite
MOA
- stimulate appetite

Question 6

“Death Rattle”

Answer 6

Palliative care
• To Stop Terminal Secretions for Noisy Respirations
Anticholinergic drugs
1. Scopolamine patch (3 mg/72 hrs)
2. Atropine (2% eye drops, sublingual)
3. Robinul (glycopyrrolate) (0.2mg IV 4x daily)