Unit 4 Lecture 29 Flashcards
What are the 3 phases of digestion?
- Cephalic phase (anticipation)
- Gastric phase (breakdown)
- Intestinal phase (controlled release)
What happens during the cephalic phase?
- prepares mouth and stomach for food
How does the cephalic phase prepare the mouth and stomach for food?
Senses of food stimulate PARASYMPATHETIC nervous system to stimulate
- salivation (facial and glossopharyngeal)
- Gastric glands to secrete gastric juices (vagus)
What are the 2 influences of the gastric phase?
Neural influence and endocrine (hormone) influences
What are the neural influences over stomach activity?
- stretch receptors and chemoreceptors (pH) signal bolus entry
- vigorous peristalsis and gastric gland secretions
- chyme periodically released into the duodenum
What are the endocrine (hormonal) influences over stomach activity?
- distention/ food in stomach -> G cells secrete gastrin -> increases gastric gland secretions, motility and causes pyloric sphincter to relax
How is gastric emptying increased?
as bolus of food enters the stomach
- stimulates contractions of lower esophageal sphincter and relaxes pyloric sphincter
What is the main function of the intestinal phase of digestion?
Controlled release of chyme
What are the 2 influences of the intestinal phase?
Neural and endocrine (hormone ) influences
What is the neural influence of the intestinal phase?
- Distension of the duodenum
- chemical contents of the chyme activates sympathetic nerves which slows gastric activity
What reflex is associated with the neural influence of the intestinal phase of digestion?
Enterogastric reflex
What is the endocrine influence of the intestinal phase?
- distension of duodenum and contents of chyme triggers hormonal release from enteroendocrine cells in duodenum
* remember small intestine cell, enteroendocrine cell secretes secretin and CCK
What are the hormones released from the enteroendocrine cells in the duodenum and what do they do?
- secretin: decreases stomach secretions
- cholecystokinin (CCK): decreases stomach emptying
What does secretin do?
stimulates secretion of sodium bicarbonate release
What does CCK do?
stimulate secretion of digestive enzyme release