Unit 2 Lecture 14 (continued) Flashcards
How does CO2 travel through the body?
released from tissue cells –> into plasma –> into red blood cells
What 2 things are formed in red blood cells?
H2CO3 (carbonic acid) and “carbaminohemoglobin”
What are the 3 modes of transport of CO2 throughout the body?
- travel in plasma as bicarbonate ions
- travel in carbaminohemoglobin
- dissolved in plasma
What is the most common way CO2 is transported?
transported in plasma as bicarbonate ions
What is carbonic anhydrase?
an enzyme that increases the rxn of CO2 out of the body
Does O2 go in or out of alveoli?
Go out of alveoli
Does CO2 go in or out of alveoli?
Go in alveoli
During internal respiration, what “shifts” across RBCs?
Chloride
How does CO2 and O2 diffuse through red blood cells during internal respiration?
CO2 goes in and O2 goes out of red blood cells
Which way does Cl- travel through red blood cells during internal respiration?
Cl- goes in
What must happen in order for Cl- to enter RBC during internal respiration?
Bicarbonate (HCO3-) must be spit out so Cl- can replace the loss in (-) charge
What is the partial pressure of O2 in oxygenated and deoxygenated blood?
oxygenated blood - 100 mmHg
deoxygenated blood- 40 mmHg
What is the partial pressure of O2 in systemic tissues cells?
40 mmHg
What is the partial pressure of CO2 in oxygenated and deoxygenated blood?
oxygenated blood - 40 mmHg
deoxygenated blood - 45 mmHg
What is the partial pressure of CO2 in systemic tissue cells?
45 mmHg
During external respiration, what “shifts’ across red blood cells?
Cl-
During external respiration, does Cl- go in or out of the rbc?
Cl- leaves the RBC
During external respiration, how does O2 and CO2 diffuse through RBCs?
O2 enters RBC
CO2 leaves RBC
What must happen in order for Cl- to leave the RBC during external respiration?
Bicarbonate (HCO3-) must enter the RBC
What is the partial pressure of O2 and CO2 in alveolar air?
PO2 - 105 mmHg
PCO2 - 40 mmHg
What describes oxygen loading at the pulmonary capillaries?
a time dependent process
Define transit time
the rate of GAS diffusion and the rate of BLOOD FLOW through the pulmonary capillaries
How long is comlete diffusion of O2?
.25 seconds
What is transit time at rest?
0.8 seconds
Is there a greater saturation of O2 in the arterial end or venous end of pulmonary capillaries?
venous end of pulmonary capillaries
