Unit 4 Lecture 28 Flashcards
Label some manifold functions of the liver?
- metabolism of carbs, proteins and lipids
- detoxifies blood by altering drugs & hormones
- removes biliruben
- releases bile salts to help digestion by emulsification of lipids
- stores fat-soluble vitamin
- stores iron, copper and vitamin B12
- pahgocytosis of worn out blood cells and bacteria
- plays a role in vit D activation
Label the blood flow through the liver
- oxygenated blood from hepatic artery and deoxygenated blood from hepatic portal vein
- liver sinusoids
- central vein
- hepatic vein
- inferior vena cava
- right atrium of heart
what are the cells of the liver?
hepatocytes
what are the spaces between hepatocytes?
sinusoids or bile canaliculi
what are the macroohages found in the liver?
kupffer cells
Label the pathway of bile?
hepatocytes -> bile canaliculi -> bile ducts -> left and right hepatic ducts -> common hepatic duct and cystic duct -> common bile duct and pancreatic duct -> hepatopancreatic ampulla -> duodenum
What are the metabolic functions of the liver?
Carb, lipid and protein metabolism
What are the 3 processes of carbohydrate metabolism?
- gluconeogenesis
- glycogenesis
- glycogenolysis
What is gluconeogenesis?
turns amino acids and triglycerides into glucose
What is glycogenesis?
turns excess glucose intp glycogen & stores it in the liver
What is glycogenolysis?
turns glycogen back into glucose as needed
What happens during lipid metabolism?
- synthesis of cholesterol and lipoproteins (HDL and LDL)
- stores some fat
- breaks down some fatty acids
What happens during protein metabolism?
- deamination
- transamination
- synthesizes
Define deamination
removes -NH2 (amine group) from amino acids so we can use what is left as an energy source
Define transamination
converts one amino acid into another