Unit 4 Lecture 28 Flashcards

1
Q

Label some manifold functions of the liver?

A
  • metabolism of carbs, proteins and lipids
  • detoxifies blood by altering drugs & hormones
  • removes biliruben
  • releases bile salts to help digestion by emulsification of lipids
  • stores fat-soluble vitamin
  • stores iron, copper and vitamin B12
  • pahgocytosis of worn out blood cells and bacteria
  • plays a role in vit D activation
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2
Q

Label the blood flow through the liver

A
  1. oxygenated blood from hepatic artery and deoxygenated blood from hepatic portal vein
  2. liver sinusoids
  3. central vein
  4. hepatic vein
  5. inferior vena cava
  6. right atrium of heart
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3
Q

what are the cells of the liver?

A

hepatocytes

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4
Q

what are the spaces between hepatocytes?

A

sinusoids or bile canaliculi

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5
Q

what are the macroohages found in the liver?

A

kupffer cells

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6
Q

Label the pathway of bile?

A

hepatocytes -> bile canaliculi -> bile ducts -> left and right hepatic ducts -> common hepatic duct and cystic duct -> common bile duct and pancreatic duct -> hepatopancreatic ampulla -> duodenum

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7
Q

What are the metabolic functions of the liver?

A

Carb, lipid and protein metabolism

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8
Q

What are the 3 processes of carbohydrate metabolism?

A
  1. gluconeogenesis
  2. glycogenesis
  3. glycogenolysis
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9
Q

What is gluconeogenesis?

A

turns amino acids and triglycerides into glucose

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10
Q

What is glycogenesis?

A

turns excess glucose intp glycogen & stores it in the liver

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11
Q

What is glycogenolysis?

A

turns glycogen back into glucose as needed

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12
Q

What happens during lipid metabolism?

A
  • synthesis of cholesterol and lipoproteins (HDL and LDL)
  • stores some fat
  • breaks down some fatty acids
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13
Q

What happens during protein metabolism?

A
  • deamination
  • transamination
  • synthesizes
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14
Q

Define deamination

A

removes -NH2 (amine group) from amino acids so we can use what is left as an energy source

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15
Q

Define transamination

A

converts one amino acid into another

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16
Q

what is synthesized during protein metabolism?

A

plasma proteins utilized in the clotting mechanism and immune system

17
Q

What are the areas of the large intestine?

A

cecum, colon, rectum and anus

18
Q

What are the cells of the large intestine and what does it secrete or absorb?

A
  • absorptive cell (absorbs water)

- goblet cell (secretes mucus)

19
Q

What are the functions of the large intestine?

A
  • haustral churning

- fermentation of undigested carbs into carbon dioxied and methane gas by bacteria

20
Q

What are the 3 reflexes of the large intestine?

A
  • gastroilial reflex
  • gastrocolic reflex
  • defecation reflex
21
Q

What is gastroilial refelx

A

when stomach is full, gastrin hormone relaxes ileocecal sphincter so small intestine will empty into large intestine

22
Q

What is gastrocolic reflex

A

when stomach fills, a strong peristaltic wave moves contents of transverse colon into rectum

23
Q

What is defecation reflex

A

when rectum fills, input to sacral spinal cord return commands to expel feces

24
Q

Label the steps of the defecation reflex

A
  1. gastrocolic reflex moves feces into rectum
  2. stretch receptors signal sacral spinal cord
  3. parasympathetic nerves contract muscles of rectum & relax internal anal sphincter
  4. external anal sphincter is voluntary controlled