Substance P/Neurokinin 1 Receptor Antagonists Flashcards
1
Q
Medications
A
“-pitant”
- Aprepitant
- Rolapitant
2
Q
Actions
A
-Act directly in the CNS to clock receptors associated with N/V
3
Q
Indications
A
-In combination with other agents to prevent N/V
4
Q
Contraindications
A
-Allergy
5
Q
Caution
A
-Pregnancy/lactation
6
Q
Adverse effects
A
-Anorexia, fatigue, constipation, diarrhea, liver enzyme elevation, dehydration
7
Q
Drug-drug
A
-Warfarin, hormonal contraceptives
