Anticholinergic Agents - General

Question 1

Anticholinergic Agents-MOA

Answer 1

• Block the effects of ACh

- Also called parasympatholytic agents

Question 2

Anticholinergic agents- Uses

Answer 2

• Decrease PNS activity
• Decrease GI activity and secretions (ulcers and hyperactive bowel)
• Bronchodilation (COPD)
• Relax bladder
• Decrease secretions before anesthesia
• Treatment of N/V and motion sickness

Question 3

T/F Derived by the plant Belladonna

Answer 3

True

Question 4

T/F Act by competing with ACh for the nicotinic receptors

Answer 4

False, the muscarinic receptors

Question 5

Effects of blocking the PNS

Answer 5

• Increase HR
• Decreased GI activity
• Decrease in urinary bladder tone and function
• Pupil dilation
• Cycloplegia

Question 6

Considerations for children

Answer 6

• Often used in children

- More sensitive to adverse effects

Question 7

Considerations for adults

Answer 7

• Safety precautions- NO DRIVING
• Use with caution in pregnancy
• Avoid breastfeeding

Question 8

Considerations in older adults

Answer 8

• More likely to have adverse effects
• Reduce doses
• Institute safety precautions