Carbonic Anhydrase Inhibitors Flashcards
1
Q
Medication
A
-Acetazolamide
2
Q
Action
A
- Block the effects of carbonic anhydrase; slow down the movement of hydrogen ions
- More Na and bicarbonate are lost in the urine
3
Q
Indications
A
- Adjunct to other diuretics
- Glaucoma
4
Q
Contraindications
A
- Allergy to drug, thiazides, or sufonamides
- Pregnancy/lactation
5
Q
Cautions
A
- Fluid & electrolyte imbalances
- Renal or hepatic disease
- Respiratory acidosis/COPD
6
Q
Adverse effects
A
- Metabolic acidosis
- Hypokalemia
- Effects on the CNS r/t electrolyte changes: paresthesias of extremities, confusion, drowsiness
7
Q
Drug-Drug interactions
A
-Salicylates and lithium: increased excretion, monitor lithium levels
