Cholesterol Absorption Inhibitors Flashcards
1
Q
Medication
A
-Ezetimibe
2
Q
Action
A
- Works in the small intestine to decrease absorption of dietary cholesterol
- Less cholesterol is circulated to the liver
3
Q
Indications
A
- Lower serum cholesterol levels
- Used adjunct with statin
4
Q
Contraindications
A
-Allergy
5
Q
Cautions
A
-Pregnancy and lactation
6
Q
Adverse effects
A
- GI: abdominal pain and diarrhea
- CNS: HA, dizziness, fatigue
- URI
- Muscle aches, back pain
7
Q
Drug-Drug interactions
A
- Cholestyramine, fenofibrate, gemfibrozil, or antacids: increase ezetimibe levels
- Cyclosporine: increase in toxicity risk
- Fibrates: Increased risk for cholelithiasis
- Warfarin: Increase in warfarin levels
8
Q
Assessment
A
- History: Contraindications, liver fx
- Physical: CNS, lung sounds, abdomen
- Labs: cholesterol, lipids
9
Q
Nursing diagnoses
A
- Disturbed sensory perception
- Acute pain
- Deficient knowledge
10
Q
Implementation
A
- Monitor serum lab levels before and during therapy
- Lifestyle changes
- Monitor for infection
- Comfort and safety measures
- Provide pt teaching
11
Q
Implementation
A
- Monitor serum lab levels before and during therapy
- Lifestyle changes
- Monitor for infection
- Comfort and safety measures
- Provide pt teaching
12
Q
Evaluation
A
- Evaluate response to drug
- Evaluate effectiveness of the teaching plan
- Evaluate the effectiveness of comfort and safety measures/ compliance with regimen
