Skin: 19.4: Pigment and Melanocyte Disorders Flashcards
1
Q
Where are melanocytes found?
A
in the basal layer
2
Q
What is the precursor molecule for melanin?
A
tyrosine
3
Q
From what do the melanocytes derive?
A
neural crest cells
4
Q
What causes vitiligo?
A
localized autoimmune destruction of melanocytes
5
Q
What enzyme defect causes albinism?
A
tyrosinase
6
Q
What is melasma?
A
a mask-like hyperpigmentation of the cheeks assoc. with pregnancy, OCPs
7
Q
Melanoma or nevus: hair growing from it.
A
nevus (mole)
8
Q
What is the inheritance of dysplastic nevi syndrome?
A
AD