Endocrine: 15.3: Hypothyroidism Flashcards
1
Q
What is cretinism?
A
hypothyroidism in neonates and infants
2
Q
What are the s/s of cretinism?
A
- mental retardation
- short stature/skeleton abnormalities
- course facial features
- large tongue
- hernia
3
Q
This is hypothyroidism in neonates and infants.
A
cretinism
4
Q
Name 2 antibodies present in Hashimotos that are used as markers for disease but do not cause the pathology.
A
- antimicrosomal Abs
- antithyroglobulin Abs
5
Q
Pts with Hashimotos have an increased risk of developing ______.
A
B cell lymphoma
6
Q
What is the cholesterol level in hypothyroidism?
A
hypercholesterolemia
7
Q
Dx?
- young female
- tender thyroid
A
subacute thyroiditis post viral infection
8
Q
What allele is assoc. with Hashimoto’s thyroiditis?
A
HLA-DR5
9
Q
Name a drug that can cause hypothyroidism.
A
lithium
10
Q
What is seen on histology in Hashimotos?
A
- germinal center formation
- chronic inflammation
- Hurthle cells
11
Q
What hormone is most commonly deficient in dyshormonogenetic goiter?
A
thyroid peroxidase
