Skin: 19.1: Inflam. Dermatoses Flashcards
What is the skin layer up against the basement membrane?
the stratum basalis
What is contained within the stratum basalis?
the skin stem cells
What layer sits on top of the stratum basalis?
the stratum spinosum
What connects the cells of the stratum spinosum together?
desmosomes
What layer of skin sits above the stratum spinosum?
the stratum granulosum
What is the most superficial skin layer?
the stratum corneum
What causes atopic dermatitis? What is it assoc. with?
type I HSR; asthma and allergic rhinitis
What’s another name for atopic dermatitis?
eczema
Where does psoriasis most often occur?
the extensor surfaces and scalp
What causes psoriasis?
excessive keratinocyte proliferation; possible autoimmune; HLA-C association
What is acanthosis?
excessive thickening of the epidermis
What is Auspit’s sign?
bleeding when psoriasis plaques are peeled away
What is the tx for psoriasis?
corticosteroids, UVA light with psoralen (PUVA), immune-modulation
What is lichen planus?
pruritic, planar, polygonal, purple papules (all the Ps in lichen Planus)
Where does lichen planus occur?
wrists, elbows, and oral mucosa
