Skin: 19.3: Epithelial Tumors Flashcards
An SK is made of what cells?
squamous epi
What’s another name for an SK?
barnacle of life
What are pseudocysts in SKs?
round fibrin products on histology
Sudden onset of multiple SKs suggest?
an underlying carcinoma, usu of the GI tract
Name 3 risk factors for basal cell carcinoma.
- sunlight
- albinism
- xeroderma pigmentosum
What is the inheritance of xeroderma pigmentosum?
auto. recessive
What is the defect in xeroderma pigmentosum?
DNA excision repair defect- can’t remove pyrimidine dimers
Where does basal cell carcinoma classically arise?
on the upper lip
Name 3 unique risk factors for SCC.
- immunosuppressive therapy
- arsenic poisoning
- chronic inflammation
AKs are precursors to?
SCC
What CA appears on the upper lip?
basal cell carcinoma
“Peripheral palisading” central area on histology?
basal cell carcinoma
Hyperkeratotic, scaly plaque on the face, back, or neck?
AK
What CA appears on the lower lip?
SCC
What is keratoacanthoma?
a well-differentiated SCC that develops w/I weeks but regresses just as quickly
