Inflammation 2.2: Chronic Inflam. Flashcards
1
Q
What are the key mediators of apoptosis?
A
caspases
2
Q
What is the key cell that defines a granuloma?
A
an epitheliod histiocyte (macs with abundant pink cytoplasm, not the normal, foamy clear cytoplasm)
3
Q
Name 5 things that cause noncaseating granulomatous inflammation.
A
- rxn to foreign material
- sarcoidosis
- beryllium exposure
- Crohns dz
- cat scratch dz (stellate shaped)
4
Q
What is the histologic feature of ulcerative colitis?
A
crypt abscesses
5
Q
What is the histologic feature of Crohs disease?
A
noncaseating granulomas
6
Q
Caseating granulomas are characteristic of?
A
TB, fungal infections
