Polycythemia (Exam 1b)

Question 1

Relative Polycythemia

Answer 1

Hemoconcentrated

You are very dehydrated so it makes you look like you have a lot of RBC’s in a percentage format

Just correct the problem. Give fluids

Question 2

Primary and Secondary Polycythemia

Answer 2

Both types of absolute polycythemia

The body actually does have over saturation of RBC’s

Question 3

Risk factors for Polycythemia

Answer 3

Chronic hypoxia (COPD)

Living at high altitudes

Long-term cigarette smoking

Familiand genetic predisposition

Long term CO2 exposure (Tunnel Workers)

Question 4

Primary Polycythemia

Answer 4

Polycythemia vera

typically > 60

More common in men (2x)

Question 5

Polycythemia vera: Patho

Answer 5

Single stem cell mutates into a cell that overproduces all blood cells except for lummphocytes

Question 6

Polycythemia Vera: Clinical Manifestations

Answer 6

-Hypertension

-Clotting problems

-Ruddy color

-Intense/painful itching intensified by heat or exposure to water

Question 7

Biggest concern in polycythemia vera is

Answer 7

Cardiovascular events: Stroke/HA from clots

Question 8

Secondary Polycythemia

Answer 8

Adaptive compensatory response to tissue hypoxia

Provide more O2 carriers by increasing RBC production

Question 9

Secondary Polycythemia Pathogenesis

Answer 9

The body is not receiving enough oxygen so the hypoxemia leads to the stimulation of erythropoietin which stimulates the bone marrow to create more RBC’s

Question 10

Clinical manifestations of secondary polycythemia

Answer 10

Increase Blood Viscosity and Increase Blood volume: Hypertension and complications of decrease blood flow

Hypermetabolism: Night sweats and weight loss

Increase RBC and H/H: Itching and pain in fingers and toes