Other Pharm (Exam 2) Flashcards
Pancreatic Enzyme Replacement
pancrelipase
What do you need to know for pancrelipase?
For CHRONIC pancreatitis only and you should take it with every meal and snack
Hyperosmotic laxative
lactulose
lactulose: MOA
Reduces blood ammonia absorption in hepatic encephalopathy
lactulose: Indications
-Reduction of ammonia absorption in hepatic encephalopathy
lactulose: NSG consideration
-PO or Enema
-Can be given to titrate by number of stools or by ammonia levels
-Not just given for high ammonia levels — must have S/S of encephalopathy
-Make sure patient is NOT hypokalemic
Do not give lactulose to patient who
just has high ammonia levels or is hypokalemic
rifaximin: MOA
-Inhibits bacterial RNA synthesis by binding to bacterial DNA (initially used as an antibiotic for GI infections)
rifaximin: Indication
Hepatic encephalopathy
rifaximin: Adverse Reactions
-Peripheral edema
-Nausea
-Ascites
-Dizziness
-Fatigue
-Pruritis
-Skin rash
-Abdominal pain
-Anemia
rifaximin: NSG considerations
-Associated with increased risk of C diff
ciprofloxacin: Indications
Used to treat UTI’s - STI’s and Anthrax
ciprofloxacin: adverse effects
Arthropathy (joint disease) Irreversible
Do not give to patient with bone pain
Do not give to patient under 12
ciprofloxacin: NSG consideration
Can have a prolonged effect and be concentrated in the neutrophils
Do not give to people with muscle and bone pain
Bactrim
sulfamethoxale and trimethoprim
