Cardiac Pharmacology (Rate and Rhythm) (Exam 3) Flashcards
Rate and Rhythm Control
Beta Blockers
Calcium Channel Blockers
Amiodarone
Adenosine
Atropine
Dofetilide
amiodarone: MOA
Prolong the action potential in all cardiac tissues
Blocks alpha-and beta=adrenergic receptors in the SNS
amiodarone: Super effective for which dysrhythmias
PSVT
AFib
amiodarone: Adverse Effects
thyroid alterations
corneal microdeposits
fat deposits
Pulmonary toxicity = fatal in 10% cases
amiodaron: BBW
Pulmonary toxicity
Hepatotoxicity
Proarrhythmic effects
Amiodarone: Drug interactions
Digoxin and warfarin increase INR
Amiodarone: Half life
Long half life last in system many days. Can take 2-3 months for them to fully go away
amiodarone: Contraindications
Severe bradycardia and heart blocks
Symptomatic Sinus Bradycardia Drug
Atropine
VAGAL INDUCED BRADYCARDIA
Atropine: class
anticholindergic
atropine: MOA
Poisons the vagus nerve; inhibits postganglionic acetylcholine receptors and direct vagolytic action
How is Atropine given
IV push only for bradycardia; 1mg every 3-5 minutes, 3g max
Atropine: Adverse Effects
Xerostomia (dry mouth)
Blurry vision
Photophobia
Flush
Hot Skin
Atropine: Nursing Implicaitons
Cardiac monitoring, if does not work, give second dose
Drug used for PSVT and Sinus Tach
Adenosine
Adenosine: MOA
Slows the conduction time through the AV node
Adenosine: NSG consideration
Very short half life (multiple doses)
Causes short burst of asystole until sinus rhythm returns
ONLY GIVEN IV
Adenosine: Given
6mg IVP, if have not converted give 12 mg IVP, can give 3rd time 12 mg IVP
Always follow with rapid normal saline flush or 2 saline flushes
3 way stop cock
Dofetilide: Class
Antidysrhythmic
Dofetilide: MOA
Blocks the cardiac ion channel carrying potassium current
Conversion from afib/aflutter to NSR
Dofetilide: Indication
Conversion off afib/aflutter to NSR
Can be taken permanently
Dofetilide: Side effects
TORSADES
SVT
Dofetilide: NSG considrations
Maintenance drug but is started in hospital with ECG due to risk of Torsades
Do not give to patients with long QT intervals or other drugs that prolong OT interval
What drug do you give for PSVT
Adenosine
Push quickly because of short half life
6mg , 12 mg 3rd 12mg
What drug do you give PSVT, RVR, or Afib
Amiodarone