Pharm Small Group - Infectious Diseases Flashcards
What is amoxicillin used prophylactically for?
Endocarditis prophylaxis during respiratory tract or dental procedures.
If amoxicillin was being used prophylactically in a newly aquired pneumonia case, what is the next choice?
Respiratory Fluoroquinolones
What are the respiratory fluoroquinolones used as 2nd line in outpatients and 1st line for inpatients?
3rd Gen: Levofloxacin
4th Gen: Moxifloxacin
Gemifloxacin
Recommended Empirical Antibiotics for C.A.P. in outpatient treatment of previously healthy pt and no use of anti-microbials in the last 3 months of treatment: (2)
A macrolide
Doxyclycline
Recommended Empirical Antibiotics for C.A.P. in outpatient treatment with presence of comorbidities, immunesuppressed, or have used antimicrobials within the past 3 months: (2)
1) Respiratory Floroquinelone
2) Beta Lactam + Macrolide
Recommended Empirical Antibiotics for C.A.P. in In patients; Non-ICU treatment
1) Respiratory Floroquinelone
2) Beta Lactam + Macrolide
Recommended Empirical Antibiotics for C.A.P. for In Patients; ICU treatment
1) Beta Lactam plus either Azithromycin or Respiratory Floroquinelone
2) Penicillin Patients: Respiratory Fluoroquinelone and Aztreonam
Which fluoroquinolone’s are considered respiratory?
Levofloxacin
Mixofloxacin
Gemifloxacin
Which antimicrobials are recommended for S.Pneumonia non-penicillin resistant?
Penicillin G
Amoxicillin
Which antimicrobials are recommended for S.Pneumonia penicillin resistant?
Agents chosen based on susceptibility including Ceftriaxone, Cefotaxime, and Fluoroquinolones
Which antimicrobial is used for H.Influenza non B lactamase producing?
Amoxicillin
Which antimicrobial is used for H.Influenza B lactamase producing?
- 2nd or 3rd generation cephalosporin
- Amoxicillin-clavulanate
Which antimicrobial is used for S. Aureus methicillin susceptible
Antistaphylococcal penicillin (Nafcillin, Oxacillin, Flucoxacillin)
Which antimicrobial is used for S.Aureus methicillin resistant?
Vancomycin or Linolezid
What is the recommended treatment for C.Difficile infections?
Oral metronidazol and oral vancomycin have similar efficacy, but metronidazole is the DOC bc of cost and risk of selection for vanc-resistant enterococci with oral vanc.
